PMC:7556165 / 32562-32860 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7556165","sourcedb":"PMC","sourceid":"7556165","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7556165","text":"ACE2 might also modulate lung inflammation via the bradykinin-DABK/BKB1R axis. In fact, decreased ACE2 function in mouse lungs caused increased activity of the DABK axis and triggered a proinflammatory cytokine storm (CXCL5, MIP2, KC, and TNF-α), leading to pulmonary collapse (Sodhi et al., 2018).","tracks":[{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T119","span":{"begin":51,"end":61},"obj":"Chemical"},{"id":"T120","span":{"begin":218,"end":223},"obj":"Chemical"}],"attributes":[{"id":"A119","pred":"chebi_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/CHEBI_3165"},{"id":"A120","pred":"chebi_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/CHEBI_138180"},{"subj":"T119","pred":"source","obj":"LitCovid-sample-CHEBI"},{"subj":"T120","pred":"source","obj":"LitCovid-sample-CHEBI"}]},{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T88","span":{"begin":115,"end":120},"obj":"Species"}],"attributes":[{"id":"A88","pred":"ncbi_taxonomy_id","subj":"T88","obj":"NCBItxid:10090"},{"id":"A89","pred":"ncbi_taxonomy_id","subj":"T88","obj":"NCBItxid:10088"},{"subj":"T88","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T200","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T201","span":{"begin":79,"end":298},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T200","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T201","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T132","span":{"begin":25,"end":29},"obj":"Body_part"}],"attributes":[{"id":"A132","pred":"uberon_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T132","pred":"source","obj":"LitCovid-sample-PD-UBERON"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"900","span":{"begin":0,"end":4},"obj":"Gene"},{"id":"901","span":{"begin":67,"end":72},"obj":"Gene"},{"id":"902","span":{"begin":98,"end":102},"obj":"Gene"},{"id":"903","span":{"begin":218,"end":223},"obj":"Gene"},{"id":"904","span":{"begin":225,"end":229},"obj":"Gene"},{"id":"905","span":{"begin":239,"end":244},"obj":"Gene"},{"id":"906","span":{"begin":115,"end":120},"obj":"Species"},{"id":"907","span":{"begin":25,"end":42},"obj":"Disease"}],"attributes":[{"id":"A901","pred":"pubann:denotes","subj":"901","obj":"Gene:623"},{"id":"A905","pred":"pubann:denotes","subj":"905","obj":"Gene:21926"},{"id":"A902","pred":"pubann:denotes","subj":"902","obj":"Gene:70008"},{"id":"A900","pred":"pubann:denotes","subj":"900","obj":"Gene:59272"},{"id":"A907","pred":"pubann:denotes","subj":"907","obj":"MESH:D011014"},{"id":"A906","pred":"pubann:denotes","subj":"906","obj":"Tax:10090"},{"id":"A904","pred":"pubann:denotes","subj":"904","obj":"Gene:20310"},{"id":"A903","pred":"pubann:denotes","subj":"903","obj":"Gene:20311"},{"subj":"900","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"901","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"902","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"903","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"904","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"905","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"906","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"907","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T2521","span":{"begin":0,"end":4},"obj":"Protein"},{"id":"T2522","span":{"begin":51,"end":61},"obj":"Protein"},{"id":"T2559","span":{"begin":98,"end":102},"obj":"Protein"},{"id":"T2560","span":{"begin":225,"end":229},"obj":"Protein"}],"attributes":[{"id":"A2521","pred":"uniprot_id","subj":"T2521","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2522","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q91XK5"},{"id":"A2523","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q90WZ1"},{"id":"A2524","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q90W88"},{"id":"A2525","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q90W16"},{"id":"A2526","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q7T3L1"},{"id":"A2527","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q7M4P1"},{"id":"A2528","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q6S9I1"},{"id":"A2529","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q6PAU9"},{"id":"A2530","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q53EQ0"},{"id":"A2531","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q32MX7"},{"id":"A2532","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/Q2KJ62"},{"id":"A2533","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P86627"},{"id":"A2534","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P86156"},{"id":"A2535","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P84895"},{"id":"A2536","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P84825"},{"id":"A2537","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P84697"},{"id":"A2538","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P84696"},{"id":"A2539","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P84695"},{"id":"A2540","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P83857"},{"id":"A2541","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P83856"},{"id":"A2542","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P83060"},{"id":"A2543","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P83055"},{"id":"A2544","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P0DM76"},{"id":"A2545","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P08934"},{"id":"A2546","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P08933"},{"id":"A2547","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01047"},{"id":"A2548","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01046"},{"id":"A2549","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01045"},{"id":"A2550","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01044"},{"id":"A2551","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01043"},{"id":"A2552","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/P01042"},{"id":"A2553","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/O08677"},{"id":"A2554","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/O08676"},{"id":"A2555","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/C9JEX1"},{"id":"A2556","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/B2RCR2"},{"id":"A2557","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/A8K474"},{"id":"A2558","pred":"uniprot_id","subj":"T2522","obj":"https://www.uniprot.org/uniprot/A0A088MIT0"},{"id":"A2559","pred":"uniprot_id","subj":"T2559","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2560","pred":"uniprot_id","subj":"T2560","obj":"https://www.uniprot.org/uniprot/Q5WA60"},{"id":"A2561","pred":"uniprot_id","subj":"T2560","obj":"https://www.uniprot.org/uniprot/P30348"},{"id":"A2562","pred":"uniprot_id","subj":"T2560","obj":"https://www.uniprot.org/uniprot/P10889"},{"subj":"T2521","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T2522","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T2559","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T2560","pred":"source","obj":"LitCovid-sample-UniProt"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T96","span":{"begin":103,"end":111},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"}],"attributes":[{"subj":"T96","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T288","span":{"begin":25,"end":29},"obj":"Body_part"},{"id":"T289","span":{"begin":73,"end":77},"obj":"Body_part"},{"id":"T290","span":{"begin":121,"end":126},"obj":"Body_part"},{"id":"T291","span":{"begin":165,"end":169},"obj":"Body_part"},{"id":"T292","span":{"begin":202,"end":210},"obj":"Body_part"}],"attributes":[{"id":"A291","pred":"fma_id","subj":"T291","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A292","pred":"fma_id","subj":"T292","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A289","pred":"fma_id","subj":"T289","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A288","pred":"fma_id","subj":"T288","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A290","pred":"fma_id","subj":"T290","obj":"http://purl.org/sig/ont/fma/fma68877"},{"subj":"T288","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T289","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T290","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T291","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T292","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T92","span":{"begin":30,"end":42},"obj":"Disease"}],"attributes":[{"id":"A92","pred":"mondo_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"subj":"T92","pred":"source","obj":"LitCovid-sample-PD-MONDO"}]},{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T122","span":{"begin":25,"end":29},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"},{"id":"T123","span":{"begin":121,"end":126},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"attributes":[{"subj":"T122","pred":"source","obj":"LitCovid-sample-PD-MAT"},{"subj":"T123","pred":"source","obj":"LitCovid-sample-PD-MAT"}]},{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T87","span":{"begin":30,"end":42},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"attributes":[{"subj":"T87","pred":"source","obj":"LitCovid-sample-PD-GO-BP-0"}]},{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T37","span":{"begin":202,"end":216},"obj":"Phenotype"}],"attributes":[{"id":"A37","pred":"hp_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"subj":"T37","pred":"source","obj":"LitCovid-sample-PD-HP"}]},{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T90","span":{"begin":30,"end":42},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"attributes":[{"subj":"T90","pred":"source","obj":"LitCovid-sample-GO-BP"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T40","span":{"begin":202,"end":216},"obj":"Phenotype"}],"attributes":[{"id":"A40","pred":"hp_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"900","span":{"begin":0,"end":4},"obj":"Gene"},{"id":"901","span":{"begin":67,"end":72},"obj":"Gene"},{"id":"902","span":{"begin":98,"end":102},"obj":"Gene"},{"id":"903","span":{"begin":218,"end":223},"obj":"Gene"},{"id":"904","span":{"begin":225,"end":229},"obj":"Gene"},{"id":"905","span":{"begin":239,"end":244},"obj":"Gene"},{"id":"906","span":{"begin":115,"end":120},"obj":"Species"},{"id":"907","span":{"begin":25,"end":42},"obj":"Disease"}],"attributes":[{"id":"A900","pred":"tao:has_database_id","subj":"900","obj":"Gene:59272"},{"id":"A901","pred":"tao:has_database_id","subj":"901","obj":"Gene:623"},{"id":"A902","pred":"tao:has_database_id","subj":"902","obj":"Gene:70008"},{"id":"A903","pred":"tao:has_database_id","subj":"903","obj":"Gene:20311"},{"id":"A904","pred":"tao:has_database_id","subj":"904","obj":"Gene:20310"},{"id":"A905","pred":"tao:has_database_id","subj":"905","obj":"Gene:21926"},{"id":"A906","pred":"tao:has_database_id","subj":"906","obj":"Tax:10090"},{"id":"A907","pred":"tao:has_database_id","subj":"907","obj":"MESH:D011014"},{"subj":"900","pred":"source","obj":"LitCovid-PubTator"},{"subj":"901","pred":"source","obj":"LitCovid-PubTator"},{"subj":"902","pred":"source","obj":"LitCovid-PubTator"},{"subj":"903","pred":"source","obj":"LitCovid-PubTator"},{"subj":"904","pred":"source","obj":"LitCovid-PubTator"},{"subj":"905","pred":"source","obj":"LitCovid-PubTator"},{"subj":"906","pred":"source","obj":"LitCovid-PubTator"},{"subj":"907","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T200","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T201","span":{"begin":79,"end":298},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T200","pred":"source","obj":"LitCovid-sentences"},{"subj":"T201","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sample-CHEBI","color":"#ec93ab","default":true},{"id":"LitCovid-sample-PD-NCBITaxon","color":"#93c5ec"},{"id":"LitCovid-sample-sentences","color":"#dfec93"},{"id":"LitCovid-sample-PD-UBERON","color":"#de93ec"},{"id":"LitCovid-sample-Pubtator","color":"#93ecc4"},{"id":"LitCovid-sample-UniProt","color":"#ecaa93"},{"id":"LitCovid-sample-PD-IDO","color":"#9395ec"},{"id":"LitCovid-sample-PD-FMA","color":"#afec93"},{"id":"LitCovid-sample-PD-MONDO","color":"#ec93c9"},{"id":"LitCovid-sample-PD-MAT","color":"#93e3ec"},{"id":"LitCovid-sample-PD-GO-BP-0","color":"#ecdb93"},{"id":"LitCovid-sample-PD-HP","color":"#c193ec"},{"id":"LitCovid-sample-GO-BP","color":"#93eca7"},{"id":"LitCovid-PD-HP","color":"#ec9399"},{"id":"LitCovid-PubTator","color":"#93b3ec"},{"id":"LitCovid-sentences","color":"#cdec93"}]}]}}