PMC:7556165 / 2957-3425 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7556165","sourcedb":"PMC","sourceid":"7556165","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7556165","text":"ardiovascular disease, particularly arterial hypertension and congestive heart failure. At present, ACE inhibitors are among the most widely prescribed drugs worldwide.\nIn 2000 a novel ACE-like enzyme, eventually named ACE2, was discovered. It showed a different substrate selectively, and in particular it could not activate angiotensin I. At the same time, it was not a target of classical ACE inhibitors. Investigations were therefore started, aiming at 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