PMC:7556165 / 24295-24809
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7556165","sourcedb":"PMC","sourceid":"7556165","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7556165","text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015).","tracks":[{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T89","span":{"begin":71,"end":75},"obj":"Chemical"},{"id":"T90","span":{"begin":278,"end":285},"obj":"Chemical"}],"attributes":[{"id":"A89","pred":"chebi_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T89","pred":"source","obj":"LitCovid-sample-CHEBI"},{"subj":"T90","pred":"source","obj":"LitCovid-sample-CHEBI"}]},{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T71","span":{"begin":112,"end":117},"obj":"Species"},{"id":"T72","span":{"begin":300,"end":305},"obj":"Species"}],"attributes":[{"id":"A71","pred":"ncbi_taxonomy_id","subj":"T71","obj":"NCBItxid:9606"},{"id":"A72","pred":"ncbi_taxonomy_id","subj":"T72","obj":"NCBItxid:9606"},{"subj":"T71","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T72","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T153","span":{"begin":0,"end":108},"obj":"Sentence"},{"id":"T154","span":{"begin":109,"end":246},"obj":"Sentence"},{"id":"T155","span":{"begin":247,"end":514},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T153","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T154","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T155","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T102","span":{"begin":19,"end":35},"obj":"Body_part"},{"id":"T103","span":{"begin":80,"end":107},"obj":"Body_part"},{"id":"T104","span":{"begin":118,"end":124},"obj":"Body_part"},{"id":"T105","span":{"begin":363,"end":369},"obj":"Body_part"}],"attributes":[{"id":"A102","pred":"uberon_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/UBERON_0000949"},{"id":"A103","pred":"uberon_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/UBERON_0000474"},{"id":"A104","pred":"uberon_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"A105","pred":"uberon_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/UBERON_0003891"},{"subj":"T102","pred":"source","obj":"LitCovid-sample-PD-UBERON"},{"subj":"T103","pred":"source","obj":"LitCovid-sample-PD-UBERON"},{"subj":"T104","pred":"source","obj":"LitCovid-sample-PD-UBERON"},{"subj":"T105","pred":"source","obj":"LitCovid-sample-PD-UBERON"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"648","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"649","span":{"begin":126,"end":130},"obj":"Gene"},{"id":"650","span":{"begin":273,"end":277},"obj":"Gene"},{"id":"651","span":{"begin":112,"end":117},"obj":"Species"},{"id":"652","span":{"begin":300,"end":305},"obj":"Species"},{"id":"653","span":{"begin":306,"end":313},"obj":"Disease"}],"attributes":[{"id":"A648","pred":"pubann:denotes","subj":"648","obj":"Gene:59272"},{"id":"A649","pred":"pubann:denotes","subj":"649","obj":"Gene:59272"},{"id":"A650","pred":"pubann:denotes","subj":"650","obj":"Gene:59272"},{"id":"A651","pred":"pubann:denotes","subj":"651","obj":"Tax:9606"},{"id":"A652","pred":"pubann:denotes","subj":"652","obj":"Tax:9606"},{"id":"A653","pred":"pubann:denotes","subj":"653","obj":"MESH:D010051"},{"subj":"648","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"649","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"650","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"651","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"652","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"653","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1988","span":{"begin":37,"end":41},"obj":"Protein"},{"id":"T1989","span":{"begin":126,"end":130},"obj":"Protein"},{"id":"T1990","span":{"begin":273,"end":277},"obj":"Protein"}],"attributes":[{"id":"A1988","pred":"uniprot_id","subj":"T1988","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1989","pred":"uniprot_id","subj":"T1989","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1990","pred":"uniprot_id","subj":"T1990","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"subj":"T1988","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T1989","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T1990","pred":"source","obj":"LitCovid-sample-UniProt"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T61","span":{"begin":87,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0000003"},{"id":"T62","span":{"begin":171,"end":176},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T63","span":{"begin":214,"end":222},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T64","span":{"begin":392,"end":397},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"attributes":[{"subj":"T61","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T62","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T63","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T64","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T212","span":{"begin":19,"end":35},"obj":"Body_part"},{"id":"T213","span":{"begin":87,"end":107},"obj":"Body_part"},{"id":"T214","span":{"begin":118,"end":124},"obj":"Body_part"},{"id":"T215","span":{"begin":163,"end":176},"obj":"Body_part"},{"id":"T216","span":{"begin":171,"end":176},"obj":"Body_part"},{"id":"T217","span":{"begin":278,"end":285},"obj":"Body_part"},{"id":"T218","span":{"begin":363,"end":369},"obj":"Body_part"},{"id":"T219","span":{"begin":382,"end":397},"obj":"Body_part"},{"id":"T220","span":{"begin":392,"end":397},"obj":"Body_part"}],"attributes":[{"id":"A219","pred":"fma_id","subj":"T219","obj":"http://purl.org/sig/ont/fma/fma18718"},{"id":"A213","pred":"fma_id","subj":"T213","obj":"http://purl.org/sig/ont/fma/fma7160"},{"id":"A215","pred":"fma_id","subj":"T215","obj":"http://purl.org/sig/ont/fma/fma72298"},{"id":"A212","pred":"fma_id","subj":"T212","obj":"http://purl.org/sig/ont/fma/fma9668"},{"id":"A214","pred":"fma_id","subj":"T214","obj":"http://purl.org/sig/ont/fma/fma7210"},{"id":"A218","pred":"fma_id","subj":"T218","obj":"http://purl.org/sig/ont/fma/fma81494"},{"id":"A217","pred":"fma_id","subj":"T217","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A220","pred":"fma_id","subj":"T220","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A216","pred":"fma_id","subj":"T216","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T212","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T213","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T214","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T215","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T216","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T217","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T218","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T219","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T220","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T85","span":{"begin":19,"end":35},"obj":"http://purl.obolibrary.org/obo/MAT_0000021"},{"id":"T86","span":{"begin":71,"end":75},"obj":"http://purl.obolibrary.org/obo/MAT_0000029"},{"id":"T87","span":{"begin":80,"end":107},"obj":"http://purl.obolibrary.org/obo/MAT_0000028"},{"id":"T88","span":{"begin":118,"end":124},"obj":"http://purl.obolibrary.org/obo/MAT_0000132"}],"attributes":[{"subj":"T85","pred":"source","obj":"LitCovid-sample-PD-MAT"},{"subj":"T86","pred":"source","obj":"LitCovid-sample-PD-MAT"},{"subj":"T87","pred":"source","obj":"LitCovid-sample-PD-MAT"},{"subj":"T88","pred":"source","obj":"LitCovid-sample-PD-MAT"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"648","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"649","span":{"begin":126,"end":130},"obj":"Gene"},{"id":"650","span":{"begin":273,"end":277},"obj":"Gene"},{"id":"651","span":{"begin":112,"end":117},"obj":"Species"},{"id":"652","span":{"begin":300,"end":305},"obj":"Species"},{"id":"653","span":{"begin":306,"end":313},"obj":"Disease"}],"attributes":[{"id":"A648","pred":"tao:has_database_id","subj":"648","obj":"Gene:59272"},{"id":"A649","pred":"tao:has_database_id","subj":"649","obj":"Gene:59272"},{"id":"A650","pred":"tao:has_database_id","subj":"650","obj":"Gene:59272"},{"id":"A651","pred":"tao:has_database_id","subj":"651","obj":"Tax:9606"},{"id":"A652","pred":"tao:has_database_id","subj":"652","obj":"Tax:9606"},{"id":"A653","pred":"tao:has_database_id","subj":"653","obj":"MESH:D010051"},{"subj":"648","pred":"source","obj":"LitCovid-PubTator"},{"subj":"649","pred":"source","obj":"LitCovid-PubTator"},{"subj":"650","pred":"source","obj":"LitCovid-PubTator"},{"subj":"651","pred":"source","obj":"LitCovid-PubTator"},{"subj":"652","pred":"source","obj":"LitCovid-PubTator"},{"subj":"653","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T153","span":{"begin":0,"end":108},"obj":"Sentence"},{"id":"T154","span":{"begin":109,"end":246},"obj":"Sentence"},{"id":"T155","span":{"begin":247,"end":514},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T153","pred":"source","obj":"LitCovid-sentences"},{"subj":"T154","pred":"source","obj":"LitCovid-sentences"},{"subj":"T155","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sample-CHEBI","color":"#ec93de","default":true},{"id":"LitCovid-sample-PD-NCBITaxon","color":"#93ecdf"},{"id":"LitCovid-sample-sentences","color":"#ecc593"},{"id":"LitCovid-sample-PD-UBERON","color":"#ab93ec"},{"id":"LitCovid-sample-Pubtator","color":"#94ec93"},{"id":"LitCovid-sample-UniProt","color":"#ec93ae"},{"id":"LitCovid-sample-PD-IDO","color":"#93c8ec"},{"id":"LitCovid-sample-PD-FMA","color":"#e2ec93"},{"id":"LitCovid-sample-PD-MAT","color":"#db93ec"},{"id":"LitCovid-PubTator","color":"#93ecc1"},{"id":"LitCovid-sentences","color":"#eca793"}]}]}}