PMC:7556165 / 24295-24809 JSONTXT

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T89","span":{"begin":71,"end":75},"obj":"Chemical"},{"id":"T90","span":{"begin":278,"end":285},"obj":"Chemical"}],"attributes":[{"id":"A89","pred":"chebi_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T71","span":{"begin":112,"end":117},"obj":"Species"},{"id":"T72","span":{"begin":300,"end":305},"obj":"Species"}],"attributes":[{"id":"A71","pred":"ncbi_taxonomy_id","subj":"T71","obj":"NCBItxid:9606"},{"id":"A72","pred":"ncbi_taxonomy_id","subj":"T72","obj":"NCBItxid:9606"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T153","span":{"begin":0,"end":108},"obj":"Sentence"},{"id":"T154","span":{"begin":109,"end":246},"obj":"Sentence"},{"id":"T155","span":{"begin":247,"end":514},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T102","span":{"begin":19,"end":35},"obj":"Body_part"},{"id":"T103","span":{"begin":80,"end":107},"obj":"Body_part"},{"id":"T104","span":{"begin":118,"end":124},"obj":"Body_part"},{"id":"T105","span":{"begin":363,"end":369},"obj":"Body_part"}],"attributes":[{"id":"A105","pred":"uberon_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/UBERON_0003891"},{"id":"A104","pred":"uberon_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"A102","pred":"uberon_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/UBERON_0000949"},{"id":"A103","pred":"uberon_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/UBERON_0000474"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"648","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"649","span":{"begin":126,"end":130},"obj":"Gene"},{"id":"650","span":{"begin":273,"end":277},"obj":"Gene"},{"id":"651","span":{"begin":112,"end":117},"obj":"Species"},{"id":"652","span":{"begin":300,"end":305},"obj":"Species"},{"id":"653","span":{"begin":306,"end":313},"obj":"Disease"}],"attributes":[{"id":"A650","pred":"pubann:denotes","subj":"650","obj":"Gene:59272"},{"id":"A651","pred":"pubann:denotes","subj":"651","obj":"Tax:9606"},{"id":"A653","pred":"pubann:denotes","subj":"653","obj":"MESH:D010051"},{"id":"A648","pred":"pubann:denotes","subj":"648","obj":"Gene:59272"},{"id":"A649","pred":"pubann:denotes","subj":"649","obj":"Gene:59272"},{"id":"A652","pred":"pubann:denotes","subj":"652","obj":"Tax:9606"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1988","span":{"begin":37,"end":41},"obj":"Protein"},{"id":"T1989","span":{"begin":126,"end":130},"obj":"Protein"},{"id":"T1990","span":{"begin":273,"end":277},"obj":"Protein"}],"attributes":[{"id":"A1988","pred":"uniprot_id","subj":"T1988","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1989","pred":"uniprot_id","subj":"T1989","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1990","pred":"uniprot_id","subj":"T1990","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T61","span":{"begin":87,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0000003"},{"id":"T62","span":{"begin":171,"end":176},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T63","span":{"begin":214,"end":222},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T64","span":{"begin":392,"end":397},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T212","span":{"begin":19,"end":35},"obj":"Body_part"},{"id":"T213","span":{"begin":87,"end":107},"obj":"Body_part"},{"id":"T214","span":{"begin":118,"end":124},"obj":"Body_part"},{"id":"T215","span":{"begin":163,"end":176},"obj":"Body_part"},{"id":"T216","span":{"begin":171,"end":176},"obj":"Body_part"},{"id":"T217","span":{"begin":278,"end":285},"obj":"Body_part"},{"id":"T218","span":{"begin":363,"end":369},"obj":"Body_part"},{"id":"T219","span":{"begin":382,"end":397},"obj":"Body_part"},{"id":"T220","span":{"begin":392,"end":397},"obj":"Body_part"}],"attributes":[{"id":"A219","pred":"fma_id","subj":"T219","obj":"http://purl.org/sig/ont/fma/fma18718"},{"id":"A213","pred":"fma_id","subj":"T213","obj":"http://purl.org/sig/ont/fma/fma7160"},{"id":"A215","pred":"fma_id","subj":"T215","obj":"http://purl.org/sig/ont/fma/fma72298"},{"id":"A212","pred":"fma_id","subj":"T212","obj":"http://purl.org/sig/ont/fma/fma9668"},{"id":"A214","pred":"fma_id","subj":"T214","obj":"http://purl.org/sig/ont/fma/fma7210"},{"id":"A218","pred":"fma_id","subj":"T218","obj":"http://purl.org/sig/ont/fma/fma81494"},{"id":"A217","pred":"fma_id","subj":"T217","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A220","pred":"fma_id","subj":"T220","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A216","pred":"fma_id","subj":"T216","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T85","span":{"begin":19,"end":35},"obj":"http://purl.obolibrary.org/obo/MAT_0000021"},{"id":"T86","span":{"begin":71,"end":75},"obj":"http://purl.obolibrary.org/obo/MAT_0000029"},{"id":"T87","span":{"begin":80,"end":107},"obj":"http://purl.obolibrary.org/obo/MAT_0000028"},{"id":"T88","span":{"begin":118,"end":124},"obj":"http://purl.obolibrary.org/obo/MAT_0000132"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"648","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"649","span":{"begin":126,"end":130},"obj":"Gene"},{"id":"650","span":{"begin":273,"end":277},"obj":"Gene"},{"id":"651","span":{"begin":112,"end":117},"obj":"Species"},{"id":"652","span":{"begin":300,"end":305},"obj":"Species"},{"id":"653","span":{"begin":306,"end":313},"obj":"Disease"}],"attributes":[{"id":"A648","pred":"tao:has_database_id","subj":"648","obj":"Gene:59272"},{"id":"A649","pred":"tao:has_database_id","subj":"649","obj":"Gene:59272"},{"id":"A650","pred":"tao:has_database_id","subj":"650","obj":"Gene:59272"},{"id":"A651","pred":"tao:has_database_id","subj":"651","obj":"Tax:9606"},{"id":"A652","pred":"tao:has_database_id","subj":"652","obj":"Tax:9606"},{"id":"A653","pred":"tao:has_database_id","subj":"653","obj":"MESH:D010051"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T153","span":{"begin":0,"end":108},"obj":"Sentence"},{"id":"T154","span":{"begin":109,"end":246},"obj":"Sentence"},{"id":"T155","span":{"begin":247,"end":514},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"With regard to the endocrine system, ACE2 expression was found in both male and female reproductive systems. In human testis, ACE2 was localized to the Leydig and Sertoli cells, and might be involved in testicular function (Douglas et al., 2004). At present, no data about ACE2 protein expression is human ovaries is available, although evidence of expression in stroma, theca, and granulosa cells has been reported in other species (Tonellotto dos Santos et al., 2012; Barreta et al., 2015; Pereira et al., 2015)."}