PMC:7556165 / 14157-14451 JSONTXT

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T68","span":{"begin":26,"end":33},"obj":"Chemical"}],"attributes":[{"id":"A68","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T42","span":{"begin":129,"end":134},"obj":"Species"}],"attributes":[{"id":"A42","pred":"ncbi_taxonomy_id","subj":"T42","obj":"NCBItxid:9606"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T95","span":{"begin":35,"end":202},"obj":"Sentence"},{"id":"T96","span":{"begin":203,"end":266},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"426","span":{"begin":21,"end":25},"obj":"Gene"},{"id":"427","span":{"begin":85,"end":89},"obj":"Gene"},{"id":"428","span":{"begin":110,"end":114},"obj":"Gene"},{"id":"429","span":{"begin":166,"end":170},"obj":"Gene"},{"id":"430","span":{"begin":234,"end":238},"obj":"Gene"},{"id":"431","span":{"begin":254,"end":258},"obj":"Gene"},{"id":"436","span":{"begin":129,"end":134},"obj":"Species"}],"attributes":[{"id":"A426","pred":"pubann:denotes","subj":"426","obj":"Gene:2146"},{"id":"A427","pred":"pubann:denotes","subj":"427","obj":"Gene:59272"},{"id":"A428","pred":"pubann:denotes","subj":"428","obj":"Gene:59272"},{"id":"A429","pred":"pubann:denotes","subj":"429","obj":"Gene:2146"},{"id":"A430","pred":"pubann:denotes","subj":"430","obj":"Gene:2146"},{"id":"A431","pred":"pubann:denotes","subj":"431","obj":"Gene:59272"},{"id":"A436","pred":"pubann:denotes","subj":"436","obj":"Tax:9606"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1699","span":{"begin":85,"end":89},"obj":"Protein"},{"id":"T1700","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T1701","span":{"begin":254,"end":258},"obj":"Protein"}],"attributes":[{"id":"A1699","pred":"uniprot_id","subj":"T1699","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1700","pred":"uniprot_id","subj":"T1700","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1701","pred":"uniprot_id","subj":"T1701","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T71","span":{"begin":26,"end":33},"obj":"Body_part"},{"id":"T72","span":{"begin":267,"end":276},"obj":"Body_part"}],"attributes":[{"id":"A71","pred":"fma_id","subj":"T71","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A72","pred":"fma_id","subj":"T72","obj":"http://purl.org/sig/ont/fma/fma67526"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T48","span":{"begin":135,"end":139},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0009989"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-PubTator","denotations":[{"id":"426","span":{"begin":21,"end":25},"obj":"Gene"},{"id":"427","span":{"begin":85,"end":89},"obj":"Gene"},{"id":"428","span":{"begin":110,"end":114},"obj":"Gene"},{"id":"429","span":{"begin":166,"end":170},"obj":"Gene"},{"id":"430","span":{"begin":234,"end":238},"obj":"Gene"},{"id":"431","span":{"begin":254,"end":258},"obj":"Gene"},{"id":"436","span":{"begin":129,"end":134},"obj":"Species"}],"attributes":[{"id":"A426","pred":"tao:has_database_id","subj":"426","obj":"Gene:2146"},{"id":"A427","pred":"tao:has_database_id","subj":"427","obj":"Gene:59272"},{"id":"A428","pred":"tao:has_database_id","subj":"428","obj":"Gene:59272"},{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"Gene:2146"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"Gene:2146"},{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"Gene:59272"},{"id":"A436","pred":"tao:has_database_id","subj":"436","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}

{"project":"LitCovid-sentences","denotations":[{"id":"T95","span":{"begin":35,"end":202},"obj":"Sentence"},{"id":"T96","span":{"begin":203,"end":266},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"s constituted by the EZH2 protein. In agreement with the inverse correlation between ACE2 level and H3K27me3, ACE2 expression in human ESCs was upregulated following EZH2 knock-out (Li Y. et al., 2020). On the other side, recovery of EZH2 restored basal ACE2 levels. Chromatin immunoprecipitati"}