PMC:7556165 / 118-422 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T2","span":{"begin":13,"end":16},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T3","span":{"begin":84,"end":87},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A2","pred":"meddra_id","subj":"T2","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A3","pred":"meddra_id","subj":"T3","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T5","span":{"begin":89,"end":177},"obj":"Sentence"},{"id":"T6","span":{"begin":178,"end":300},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T1","span":{"begin":159,"end":163},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"48","span":{"begin":13,"end":16},"obj":"Gene"},{"id":"49","span":{"begin":84,"end":87},"obj":"Gene"},{"id":"50","span":{"begin":89,"end":93},"obj":"Gene"},{"id":"51","span":{"begin":178,"end":182},"obj":"Gene"},{"id":"68","span":{"begin":229,"end":233},"obj":"Gene"},{"id":"77","span":{"begin":159,"end":176},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"pubann:denotes","subj":"48","obj":"Gene:1636"},{"id":"A49","pred":"pubann:denotes","subj":"49","obj":"Gene:1636"},{"id":"A50","pred":"pubann:denotes","subj":"50","obj":"Gene:59272"},{"id":"A51","pred":"pubann:denotes","subj":"51","obj":"Gene:59272"},{"id":"A68","pred":"pubann:denotes","subj":"68","obj":"Gene:159371"},{"id":"A77","pred":"pubann:denotes","subj":"77","obj":"MESH:D011014"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T18","span":{"begin":13,"end":16},"obj":"Protein"},{"id":"T43","span":{"begin":84,"end":87},"obj":"Protein"},{"id":"T68","span":{"begin":89,"end":93},"obj":"Protein"},{"id":"T69","span":{"begin":178,"end":182},"obj":"Protein"}],"attributes":[{"id":"A18","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A19","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A20","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A21","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A22","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A23","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A24","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A25","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A26","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A27","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A28","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A29","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A30","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A31","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A32","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A33","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A34","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A35","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A36","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A37","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A38","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A39","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A40","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A41","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A42","pred":"uniprot_id","subj":"T18","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A43","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A44","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A45","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A46","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A47","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A48","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A49","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A50","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A51","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A52","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A53","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A54","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A55","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A56","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A57","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A58","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A59","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A60","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A61","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A62","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A63","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A64","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A65","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A66","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A67","pred":"uniprot_id","subj":"T43","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A68","pred":"uniprot_id","subj":"T68","obj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related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T1","span":{"begin":159,"end":163},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T3","span":{"begin":164,"end":176},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T1","span":{"begin":159,"end":163},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T1","span":{"begin":164,"end":176},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T2","span":{"begin":209,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T3","span":{"begin":234,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T1","span":{"begin":164,"end":176},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T2","span":{"begin":209,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T3","span":{"begin":234,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":13,"end":16},"obj":"Gene"},{"id":"49","span":{"begin":84,"end":87},"obj":"Gene"},{"id":"50","span":{"begin":89,"end":93},"obj":"Gene"},{"id":"51","span":{"begin":178,"end":182},"obj":"Gene"},{"id":"68","span":{"begin":229,"end":233},"obj":"Gene"},{"id":"77","span":{"begin":159,"end":176},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Gene:1636"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:1636"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Gene:59272"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"Gene:59272"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"Gene:159371"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}

{"project":"LitCovid-sentences","denotations":[{"id":"T5","span":{"begin":89,"end":177},"obj":"Sentence"},{"id":"T6","span":{"begin":178,"end":300},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"s related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and cardioprotective effects and reduces lung inflammation. ACE2 is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Als"}