PMC:7546716 / 4073-4901
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T56 | 7-12 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T57 | 14-16 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T58 | 71-85 | Body_part | denotes | alveolar cells | http://purl.org/sig/ont/fma/fma62499 |
| T59 | 80-85 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T60 | 151-153 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T61 | 264-279 | Body_part | denotes | dendritic cells | http://purl.org/sig/ont/fma/fma273565 |
| T62 | 274-279 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T63 | 291-295 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T64 | 291-293 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T65 | 315-319 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T66 | 499-519 | Body_part | denotes | alveolar macrophages | http://purl.org/sig/ont/fma/fma83023 |
| T67 | 640-642 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T68 | 669-673 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T69 | 711-717 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T6 | 711-717 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T44 | 97-106 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T45 | 371-383 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T46 | 413-421 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T47 | 794-802 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T39 | 7-12 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T40 | 60-70 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T41 | 80-85 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T42 | 199-204 | http://purl.obolibrary.org/obo/PR_000001350 | denotes | Foxp3 |
| T43 | 220-224 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T44 | 249-254 | http://purl.obolibrary.org/obo/PR_000001013 | denotes | CD11c |
| T45 | 256-279 | http://purl.obolibrary.org/obo/CL_0000782 | denotes | myeloid dendritic cells |
| T46 | 291-295 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T47 | 310-314 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T48 | 315-319 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T49 | 482-486 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T50 | 528-529 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T51 | 623-628 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T52 | 664-668 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T53 | 669-673 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T44 | 14-16 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T46 | 151-153 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T48 | 291-293 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T50 | 640-642 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T7 | 315-329 | http://purl.obolibrary.org/obo/GO_0016049 | denotes | cell expansion |
| T8 | 371-383 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T9 | 603-618 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T18 | 0-828 | Sentence | denotes | In the lungs, IL-33 is promptly released, mainly by injured epithelial alveolar cells, following infection and cellular damage.12 Among its functions, IL-33 enhances TGFβ-mediated differentiation of Foxp3+ regulatory T (Treg) cells13 and stimulates CD11c+ myeloid dendritic cells to secrete IL-2, which drives Treg cell expansion, thus ultimately promoting resolution of inflammation.14 Individuals infected with SARS-CoV-2 who develop milder symptoms tend to have large numbers of Treg cells10 and alveolar macrophages showing a scavenger resolving (FABP4+) phenotype.15 In the presence of an adequate immune response and virus clearance, IL-33 might drive rapid Treg cell-dependent restoration of respiratory tissue homoeostasis, which probably accounts for the mild or asymptomatic forms of COVID-19 seen in most individuals. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 166 | 14-19 | Gene | denotes | IL-33 | Gene:90865 |
| 167 | 151-156 | Gene | denotes | IL-33 | Gene:90865 |
| 168 | 166-170 | Gene | denotes | TGFβ | Gene:7039 |
| 169 | 199-204 | Gene | denotes | Foxp3 | Gene:50943 |
| 170 | 249-254 | Gene | denotes | CD11c | Gene:3687 |
| 171 | 291-295 | Gene | denotes | IL-2 | Gene:3558 |
| 172 | 551-556 | Gene | denotes | FABP4 | Gene:2167 |
| 173 | 640-645 | Gene | denotes | IL-33 | Gene:90865 |
| 175 | 413-423 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 177 | 97-106 | Disease | denotes | infection | MESH:D007239 |
| 178 | 371-383 | Disease | denotes | inflammation | MESH:D007249 |
| 179 | 399-407 | Disease | denotes | infected | MESH:D007239 |
| 180 | 699-730 | Disease | denotes | respiratory tissue homoeostasis | MESH:D012140 |
| 181 | 794-802 | Disease | denotes | COVID-19 | MESH:C000657245 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 33073244-31057533-66244514 | 127-129 | 31057533 | denotes | 12 |
| 33073244-25043027-66244515 | 231-233 | 25043027 | denotes | 13 |
| 33073244-25217167-66244516 | 384-386 | 25217167 | denotes | 14 |
| 33073244-32460357-66244517 | 492-494 | 32460357 | denotes | 10 |
| 33073244-32398875-66244518 | 569-571 | 32398875 | denotes | 15 |