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PMC:7546716 / 1614-2782 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T26 102-106 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T27 395-405 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T28 495-504 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T29 536-549 Body_part denotes interleukin-6 http://purl.org/sig/ont/fma/fma264829
T30 552-554 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T31 893-901 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T32 1110-1114 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T3 102-106 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T15 102-114 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T16 131-139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 178-186 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 206-218 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T19 237-272 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T20 243-272 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T21 278-290 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T22 329-374 Disease denotes secondary haemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T23 395-425 Disease denotes macrophage activation syndrome http://purl.obolibrary.org/obo/MONDO_0015545
T24 427-430 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T25 523-526 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T26 653-661 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 697-716 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T28 749-761 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T29 833-841 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T30 868-871 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T31 902-916 Disease denotes storm syndrome http://purl.obolibrary.org/obo/MONDO_0008496
T32 925-933 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 974-977 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T34 1131-1139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T35 1162-1165 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T15 102-106 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T16 102-106 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T17 378-383 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T18 406-416 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T19 454-461 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T20 536-549 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin-6
T21 579-595 http://purl.obolibrary.org/obo/PR_000000017 denotes interferon gamma
T22 1004-1005 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 1040-1041 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 1108-1114 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T25 1148-1153 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 58-67 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T16 552-554 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T18 563-574 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T19 579-589 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T20 590-595 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 102-114 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T4 243-263 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T5 278-290 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T6 893-907 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T2 206-218 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T3 395-416 http://purl.obolibrary.org/obo/GO_0042116 denotes macrophage activation
T4 749-761 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T12 1-432 Sentence denotes Given the public health emergency, scarcity of effective antiviral therapies, and rapid evolution of lung disease associated with COVID-19, patients who are critically ill with COVID-19 and have exuberant inflammation, life-threatening acute respiratory distress syndrome, and coagulopathy, are basically treated as if they had secondary haemophagocytic lymphohistiocytosis or virus-associated macrophage activation syndrome (MAS).
T13 433-872 Sentence denotes These treatments are focused on therapies that neutralise key cytokines driving classical MAS, such as interleukin-6 ([IL]-6; eg, tocilizumab) or interferon gamma (IFNγ; eg, emapalumab).1, 2 In fact, some fatal cases of COVID-19 are accompanied not only by severe respiratory disease, but also by increased systemic inflammation as shown by higher ferritin concentrations.2 However, in many aspects, COVID-19 does not resemble typical MAS.
T14 873-1084 Sentence denotes We propose that the cytokine storm syndrome seen in COVID-19 is dissimilar to that seen in canonical MAS and should be regarded as a distinct entity and approached in a novel way reflecting its unique qualities.
T15 1086-1139 Sentence denotes Cellular immunity and T-cell polarisation in COVID-19

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
65 536-549 Gene denotes interleukin-6 Gene:3569
66 579-595 Gene denotes interferon gamma Gene:3458
67 597-601 Gene denotes IFNγ Gene:3458
68 603-605 Gene denotes eg Gene:50512
69 559-561 Gene denotes eg Gene:50512
72 141-149 Species denotes patients Tax:9606
74 102-114 Disease denotes lung disease MESH:D008171
75 131-139 Disease denotes COVID-19 MESH:C000657245
76 158-172 Disease denotes critically ill MESH:D016638
77 178-186 Disease denotes COVID-19 MESH:C000657245
78 206-218 Disease denotes inflammation MESH:D007249
79 237-272 Disease denotes acute respiratory distress syndrome MESH:D012128
80 278-290 Disease denotes coagulopathy MESH:D001778
81 329-374 Disease denotes secondary haemophagocytic lymphohistiocytosis MESH:D060085
82 395-425 Disease denotes macrophage activation syndrome MESH:D055501
83 653-661 Disease denotes COVID-19 MESH:C000657245
84 697-716 Disease denotes respiratory disease MESH:D012140
85 749-761 Disease denotes inflammation MESH:D007249
86 833-841 Disease denotes COVID-19 MESH:C000657245
87 925-933 Disease denotes COVID-19 MESH:C000657245
89 1131-1139 Disease denotes COVID-19 MESH:C000657245

2_test

Id Subject Object Predicate Lexical cue
33073244-30774631-66244503 619-620 30774631 denotes 1