PMC:7546716 / 0-708
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 20-31 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T2 | 48-52 | Body_part | denotes | heel | http://purl.org/sig/ont/fma/fma24994 |
| T3 | 87-95 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T4 | 248-256 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T5 | 258-269 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T6 | 271-273 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T7 | 439-441 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T8 | 482-487 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T9 | 547-565 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T10 | 560-565 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T11 | 688-692 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 48-52 | Body_part | denotes | heel | http://purl.obolibrary.org/obo/UBERON_0015875 |
| T2 | 688-692 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 56-64 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 109-117 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 320-328 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 615-662 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 615-648 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 688-700 | Disease | denotes | lung disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 208-209 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 282-283 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 482-487 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T4 | 547-565 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T5 | 688-692 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T6 | 688-692 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 271-273 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T3 | 439-441 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 688-700 | Phenotype | denotes | lung disease | http://purl.obolibrary.org/obo/HP_0002088 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-65 | Sentence | denotes | Imperfect storm: is interleukin-33 the Achilles heel of COVID-19? |
| T2 | 67-75 | Sentence | denotes | Abstract |
| T3 | 76-190 | Sentence | denotes | The unique cytokine signature of COVID-19 might provide clues to disease mechanisms and possible future therapies. |
| T4 | 191-410 | Sentence | denotes | Here, we propose a pathogenic model in which the alarmin cytokine, interleukin (IL)-33, is a key player in driving all stages of COVID-19 disease (ie, asymptomatic, mild–moderate, severe–critical, and chronic–fibrotic). |
| T5 | 411-701 | Sentence | denotes | In susceptible individuals, IL-33 release by damaged lower respiratory cells might induce dysregulated GATA-binding factor 3-expressing regulatory T cells, thereby breaking immune tolerance and eliciting severe acute respiratory syndrome coronavirus 2-induced autoinflammatory lung disease. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2 | 20-34 | Gene | denotes | interleukin-33 | Gene:90865 |
| 3 | 56-64 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 23 | 258-277 | Gene | denotes | interleukin (IL)-33 | Gene:90865 |
| 24 | 439-444 | Gene | denotes | IL-33 | Gene:90865 |
| 25 | 514-535 | Gene | denotes | GATA-binding factor 3 | Gene:2625 |
| 33 | 615-662 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 36 | 109-117 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 37 | 320-328 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 38 | 671-700 | Disease | denotes | autoinflammatory lung disease | MESH:D008171 |