PMC:7544943 / 22290-22609 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T49","span":{"begin":279,"end":287},"obj":"Disease"},{"id":"T50","span":{"begin":303,"end":311},"obj":"Disease"}],"attributes":[{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The noninhibition of CYP isoforms such as CYP1A2, CYP2C19, CYP2C9, CYP2D6 and CYP3A4 disclose that these molecules are not the substrate for these enzymes that resembles for the lower degradation rate of these molecules, which will make it effectively available for blocking the SARS-CoV-2 RBD Spro and SARS-CoV-2 Mpro."}

{"project":"LitCovid-PubTator","denotations":[{"id":"306","span":{"begin":42,"end":48},"obj":"Gene"},{"id":"307","span":{"begin":50,"end":57},"obj":"Gene"},{"id":"308","span":{"begin":59,"end":65},"obj":"Gene"},{"id":"309","span":{"begin":67,"end":73},"obj":"Gene"},{"id":"310","span":{"begin":78,"end":84},"obj":"Gene"},{"id":"311","span":{"begin":314,"end":318},"obj":"Gene"},{"id":"312","span":{"begin":279,"end":289},"obj":"Species"},{"id":"313","span":{"begin":303,"end":313},"obj":"Species"}],"attributes":[{"id":"A306","pred":"tao:has_database_id","subj":"306","obj":"Gene:1544"},{"id":"A307","pred":"tao:has_database_id","subj":"307","obj":"Gene:1557"},{"id":"A308","pred":"tao:has_database_id","subj":"308","obj":"Gene:1559"},{"id":"A309","pred":"tao:has_database_id","subj":"309","obj":"Gene:1565"},{"id":"A310","pred":"tao:has_database_id","subj":"310","obj":"Gene:1576"},{"id":"A311","pred":"tao:has_database_id","subj":"311","obj":"Gene:8673700"},{"id":"A312","pred":"tao:has_database_id","subj":"312","obj":"Tax:2697049"},{"id":"A313","pred":"tao:has_database_id","subj":"313","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The noninhibition of CYP isoforms such as CYP1A2, CYP2C19, CYP2C9, CYP2D6 and CYP3A4 disclose that these molecules are not the substrate for these enzymes that resembles for the lower degradation rate of these molecules, which will make it effectively available for blocking the SARS-CoV-2 RBD Spro and SARS-CoV-2 Mpro."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T23","span":{"begin":184,"end":195},"obj":"http://purl.obolibrary.org/obo/GO_0009056"}],"text":"The noninhibition of CYP isoforms such as CYP1A2, CYP2C19, CYP2C9, CYP2D6 and CYP3A4 disclose that these molecules are not the substrate for these enzymes that resembles for the lower degradation rate of these molecules, which will make it effectively available for blocking the SARS-CoV-2 RBD Spro and SARS-CoV-2 Mpro."}

{"project":"LitCovid-sentences","denotations":[{"id":"T199","span":{"begin":0,"end":319},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The noninhibition of CYP isoforms such as CYP1A2, CYP2C19, CYP2C9, CYP2D6 and CYP3A4 disclose that these molecules are not the substrate for these enzymes that resembles for the lower degradation rate of these molecules, which will make it effectively available for blocking the SARS-CoV-2 RBD Spro and SARS-CoV-2 Mpro."}