PMC:7544934 / 12990-13789
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T25 | 584-587 | https://glytoucan.org/Structures/Glycans/G00057MO | denotes | LDN |
T26 | 584-587 | https://glytoucan.org/Structures/Glycans/G31736BK | denotes | LDN |
T27 | 608-611 | https://glytoucan.org/Structures/Glycans/G00057MO | denotes | LDN |
T28 | 608-611 | https://glytoucan.org/Structures/Glycans/G31736BK | denotes | LDN |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T6 | 0-14 | Phenotype | denotes | Cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
T7 | 281-295 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
T8 | 382-388 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
292 | 74-82 | Species | denotes | patients | Tax:9606 |
293 | 241-249 | Species | denotes | patients | Tax:9606 |
294 | 452-458 | Species | denotes | murine | Tax:10090 |
295 | 348-366 | Chemical | denotes | lipopolysaccharide | MESH:D008070 |
296 | 677-680 | Chemical | denotes | MTT | MESH:C070243 |
297 | 682-738 | Chemical | denotes | 4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide | |
298 | 65-73 | Disease | denotes | COVID-19 | MESH:C000657245 |
299 | 121-130 | Disease | denotes | mortality | MESH:D003643 |
300 | 232-240 | Disease | denotes | COVID-19 | MESH:C000657245 |
301 | 382-388 | Disease | denotes | sepsis | MESH:D018805 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T108 | 0-204 | Sentence | denotes | Cytokine storm is a very commonly observed factor in most severe COVID-19 patients and also one of the leading causes of mortality (Coperchini et al., 2020; Rahmati and Moosavi, 2020; Zhang et al., 2020). |
T109 | 205-316 | Sentence | denotes | Peripheral blood of severe COVID-19 patients has also shown a high level of cytokine storm (Wu and Yang, 2020). |
T110 | 317-595 | Sentence | denotes | Keeping in mind the ability of lipopolysaccharide (LPS) to cause sepsis and triggers an uncontrolled systemic inflammatory response in murine macrophage cells (Ramos-Benitez et al., 2018), we treated macrophage cells with LPS (1 µg/ml) in the presence and absence of LDN (5 µM). |
T111 | 596-799 | Sentence | denotes | The dose of LDN chosen is non-toxic (Figure S2) as found in cell viability using MTT (4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide) assay following the standard protocol (Dogra et al., 2019). |