PMC:7543426 / 2458-3699 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T19","span":{"begin":574,"end":595},"obj":"Body_part"},{"id":"T20","span":{"begin":696,"end":702},"obj":"Body_part"},{"id":"T21","span":{"begin":704,"end":709},"obj":"Body_part"},{"id":"T22","span":{"begin":715,"end":720},"obj":"Body_part"},{"id":"T23","span":{"begin":781,"end":785},"obj":"Body_part"},{"id":"T24","span":{"begin":1089,"end":1094},"obj":"Body_part"},{"id":"T25","span":{"begin":1136,"end":1140},"obj":"Body_part"}],"attributes":[{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma7161"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma312401"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma64183"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma67498"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma256135"}],"text":"Clinical and epidemiological studies have established that COVID-19 presents as a spectrum of clinical manifestations from asymptomatic, to mild illness (up to 80% of patients), moderate (15% of patients), to severe illness (5% of patients). Increased mortality rates have been observed in older people (\u003e70 years of age) and those with comorbidities [2, 3]. Reports from individual or small autopsy case studies [4–6] or limited postmortem studies [7–9] show that SARS-CoV-2, like SARS-CoV-1 in 2003, is a multisystem disease that predominantly affects the respiratory and cardiovascular system. SARS-CoV-2 has been detected in a range of clinical samples, such as bronchoalveolar lavage fluid, sputum, feces, and blood, indicating widespread dissemination [10]. Performing whole-body autopsies in patients who die of COVID-19 remains challenging due to infection control regulations and other logistical reasons [11, 12]. There is a need for more detailed and larger autopsy case series to further define the pathological manifestations of COVID-19 [13] and determine the full extent of organ involvement. Here, we reported the whole-body postmortem examinations of 22 Italian patients who died of COVID-19, 4 of whom had no comorbidities."}

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{"project":"LitCovid-PD-CLO","denotations":[{"id":"T39","span":{"begin":80,"end":81},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T40","span":{"begin":505,"end":506},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41","span":{"begin":574,"end":595},"obj":"http://purl.obolibrary.org/obo/UBERON_0004535"},{"id":"T42","span":{"begin":574,"end":595},"obj":"http://www.ebi.ac.uk/efo/EFO_0000791"},{"id":"T43","span":{"begin":608,"end":611},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T44","span":{"begin":629,"end":630},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T45","span":{"begin":715,"end":720},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T46","span":{"begin":715,"end":720},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T47","span":{"begin":775,"end":785},"obj":"http://purl.obolibrary.org/obo/UBERON_0013702"},{"id":"T48","span":{"begin":915,"end":917},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T49","span":{"begin":933,"end":934},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T50","span":{"begin":1089,"end":1094},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T51","span":{"begin":1130,"end":1140},"obj":"http://purl.obolibrary.org/obo/UBERON_0013702"},{"id":"T52","span":{"begin":1168,"end":1170},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"}],"text":"Clinical and epidemiological studies have established that COVID-19 presents as a spectrum of clinical manifestations from asymptomatic, to mild illness (up to 80% of patients), moderate (15% of patients), to severe illness (5% of patients). Increased mortality rates have been observed in older people (\u003e70 years of age) and those with comorbidities [2, 3]. Reports from individual or small autopsy case studies [4–6] or limited postmortem studies [7–9] show that SARS-CoV-2, like SARS-CoV-1 in 2003, is a multisystem disease that predominantly affects the respiratory and cardiovascular system. SARS-CoV-2 has been detected in a range of clinical samples, such as bronchoalveolar lavage fluid, sputum, feces, and blood, indicating widespread dissemination [10]. Performing whole-body autopsies in patients who die of COVID-19 remains challenging due to infection control regulations and other logistical reasons [11, 12]. There is a need for more detailed and larger autopsy case series to further define the pathological manifestations of COVID-19 [13] and determine the full extent of organ involvement. Here, we reported the whole-body postmortem examinations of 22 Italian patients who died of COVID-19, 4 of whom had no comorbidities."}

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{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":873,"end":884},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"Clinical and epidemiological studies have established that COVID-19 presents as a spectrum of clinical manifestations from asymptomatic, to mild illness (up to 80% of patients), moderate (15% of patients), to severe illness (5% of patients). Increased mortality rates have been observed in older people (\u003e70 years of age) and those with comorbidities [2, 3]. Reports from individual or small autopsy case studies [4–6] or limited postmortem studies [7–9] show that SARS-CoV-2, like SARS-CoV-1 in 2003, is a multisystem disease that predominantly affects the respiratory and cardiovascular system. SARS-CoV-2 has been detected in a range of clinical samples, such as bronchoalveolar lavage fluid, sputum, feces, and blood, indicating widespread dissemination [10]. Performing whole-body autopsies in patients who die of COVID-19 remains challenging due to infection control regulations and other logistical reasons [11, 12]. There is a need for more detailed and larger autopsy case series to further define the pathological manifestations of COVID-19 [13] and determine the full extent of organ involvement. Here, we reported the whole-body postmortem examinations of 22 Italian patients who died of COVID-19, 4 of whom had no comorbidities."}

{"project":"LitCovid-sentences","denotations":[{"id":"T25","span":{"begin":0,"end":241},"obj":"Sentence"},{"id":"T26","span":{"begin":242,"end":358},"obj":"Sentence"},{"id":"T27","span":{"begin":359,"end":596},"obj":"Sentence"},{"id":"T28","span":{"begin":597,"end":763},"obj":"Sentence"},{"id":"T29","span":{"begin":764,"end":923},"obj":"Sentence"},{"id":"T30","span":{"begin":924,"end":1107},"obj":"Sentence"},{"id":"T31","span":{"begin":1108,"end":1241},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Clinical and epidemiological studies have established that COVID-19 presents as a spectrum of clinical manifestations from asymptomatic, to mild illness (up to 80% of patients), moderate (15% of patients), to severe illness (5% of patients). Increased mortality rates have been observed in older people (\u003e70 years of age) and those with comorbidities [2, 3]. Reports from individual or small autopsy case studies [4–6] or limited postmortem studies [7–9] show that SARS-CoV-2, like SARS-CoV-1 in 2003, is a multisystem disease that predominantly affects the respiratory and cardiovascular system. SARS-CoV-2 has been detected in a range of clinical samples, such as bronchoalveolar lavage fluid, sputum, feces, and blood, indicating widespread dissemination [10]. Performing whole-body autopsies in patients who die of COVID-19 remains challenging due to infection control regulations and other logistical reasons [11, 12]. There is a need for more detailed and larger autopsy case series to further define the pathological manifestations of COVID-19 [13] and determine the full extent of organ involvement. Here, we reported the whole-body postmortem examinations of 22 Italian patients who died of COVID-19, 4 of whom had no comorbidities."}