PMC:7543426 / 138-1508
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T13 | 764-769 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
T1 | 214-220 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
T2 | 292-296 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T3 | 324-328 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T4 | 457-468 | Body_part | denotes | body organs | http://purl.org/sig/ont/fma/fma45734 |
T5 | 457-461 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T6 | 682-689 | Body_part | denotes | Tissues | http://purl.org/sig/ont/fma/fma9637 |
T7 | 699-703 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T8 | 705-710 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
T9 | 712-717 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
T10 | 719-725 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T11 | 727-733 | Body_part | denotes | spleen | http://purl.org/sig/ont/fma/fma7196 |
T12 | 739-750 | Body_part | denotes | bone marrow | http://purl.org/sig/ont/fma/fma9608 |
T14 | 791-795 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T15 | 796-803 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T16 | 1028-1034 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T17 | 1049-1060 | Body_part | denotes | bone marrow | http://purl.org/sig/ont/fma/fma9608 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 214-220 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T2 | 292-296 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T3 | 310-316 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
T4 | 462-468 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
T5 | 699-703 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T6 | 705-710 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
T7 | 712-717 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
T8 | 719-725 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
T9 | 727-733 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
T10 | 739-750 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
T11 | 764-769 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
T12 | 791-795 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T13 | 1028-1034 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
T14 | 1049-1060 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
T15 | 1320-1326 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T2 | 66-90 | Disease | denotes | coronavirus disease-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 92-100 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T4 | 140-187 | Disease | denotes | severe acute respiratory syndrome coronavirus-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 140-173 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T6 | 189-197 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 348-356 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T8 | 435-443 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T9 | 513-521 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T10 | 613-623 | Disease | denotes | Infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T11 | 863-871 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T12 | 1092-1098 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T13 | 1103-1113 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
T14 | 1238-1246 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 1249-1258 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 292-296 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T3 | 292-296 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T4 | 310-316 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs |
T5 | 318-328 | http://purl.obolibrary.org/obo/UBERON_0013702 | denotes | Whole-body |
T6 | 462-468 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs |
T7 | 496-498 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T8 | 523-525 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T9 | 699-703 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T10 | 699-703 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T11 | 705-710 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
T12 | 705-710 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
T13 | 705-710 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
T14 | 705-710 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
T15 | 712-717 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
T16 | 712-717 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
T17 | 719-725 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T18 | 719-725 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T19 | 719-725 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T20 | 727-733 | http://purl.obolibrary.org/obo/UBERON_0002106 | denotes | spleen |
T21 | 739-743 | http://purl.obolibrary.org/obo/UBERON_0002481 | denotes | bone |
T22 | 764-769 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
T23 | 764-769 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
T24 | 791-795 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T25 | 791-795 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T26 | 1028-1034 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T27 | 1028-1034 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T28 | 1028-1034 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T29 | 1049-1053 | http://purl.obolibrary.org/obo/UBERON_0002481 | denotes | bone |
T30 | 1320-1329 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs in |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
11 | 140-187 | Species | denotes | severe acute respiratory syndrome coronavirus-2 | Tax:2697049 |
12 | 189-199 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
13 | 357-365 | Species | denotes | patients | Tax:9606 |
14 | 66-90 | Disease | denotes | coronavirus disease-2019 | MESH:C000657245 |
15 | 92-100 | Disease | denotes | COVID-19 | MESH:C000657245 |
16 | 122-130 | Disease | denotes | zoonotic | MESH:D015047 |
17 | 348-356 | Disease | denotes | COVID-19 | MESH:C000657245 |
23 | 435-445 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
24 | 499-507 | Species | denotes | patients | Tax:9606 |
25 | 513-521 | Disease | denotes | COVID-19 | MESH:C000657245 |
26 | 578-582 | Disease | denotes | died | MESH:D003643 |
27 | 613-632 | Disease | denotes | Infectious Diseases | MESH:D003141 |
33 | 1165-1173 | Species | denotes | patients | Tax:9606 |
34 | 863-871 | Disease | denotes | COVID-19 | MESH:C000657245 |
35 | 1049-1072 | Disease | denotes | bone marrow involvement | MESH:D001855 |
36 | 1078-1098 | Disease | denotes | microvascular injury | MESH:D017566 |
37 | 1103-1113 | Disease | denotes | thrombosis | MESH:D013927 |
41 | 1330-1338 | Species | denotes | patients | Tax:9606 |
42 | 1238-1258 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
43 | 1266-1285 | Disease | denotes | multisystem disease | MESH:D004194 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4 | 0-8 | Sentence | denotes | Abstract |
T5 | 10-20 | Sentence | denotes | Background |
T6 | 21-317 | Sentence | denotes | Descriptions of the pathological features of coronavirus disease-2019 (COVID-19) caused by the novel zoonotic pathogen severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emanate from tissue biopsies, case reports, and small postmortem studies restricted to the lung and specific organs. |
T7 | 318-383 | Sentence | denotes | Whole-body autopsy studies of COVID-19 patients have been sparse. |
T8 | 385-392 | Sentence | denotes | Methods |
T9 | 393-681 | Sentence | denotes | To further define the pathology caused by SARS-CoV-2 across all body organs, we performed autopsies on 22 patients with COVID-19 (18 with comorbidities and 4 without comorbidities) who died at the National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS Hospital, Rome, Italy. |
T10 | 682-785 | Sentence | denotes | Tissues from the lung, heart, liver, kidney, spleen, and bone marrow (but not the brain) were examined. |
T11 | 786-853 | Sentence | denotes | Only lung tissues were subject to transmission electron microscopy. |
T12 | 855-862 | Sentence | denotes | Results |
T13 | 863-901 | Sentence | denotes | COVID-19 caused multisystem pathology. |
T14 | 902-979 | Sentence | denotes | Pulmonary and cardiovascular involvement were dominant pathological features. |
T15 | 980-1133 | Sentence | denotes | Extrapulmonary manifestations included hepatic, kidney, splenic, and bone marrow involvement, and microvascular injury and thrombosis were also detected. |
T16 | 1134-1224 | Sentence | denotes | These findings were similar in patients with or without preexisting medical comorbidities. |
T17 | 1226-1237 | Sentence | denotes | Conclusions |
T18 | 1238-1370 | Sentence | denotes | SARS-CoV-2 infection causes multisystem disease and significant pathology in most organs in patients with and without comorbidities. |