PMC:7534795 / 64424-65935
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T259 | 114-123 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T260 | 125-135 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
T261 | 532-545 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
T262 | 532-536 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T263 | 846-855 | Body_part | denotes | Chemokine | http://purl.org/sig/ont/fma/fma241981 |
T264 | 1033-1042 | Body_part | denotes | G-protein | http://purl.org/sig/ont/fma/fma61788 |
T265 | 1065-1076 | Body_part | denotes | Interleukin | http://purl.org/sig/ont/fma/fma86578 |
T266 | 1137-1147 | Body_part | denotes | fatty acid | http://purl.org/sig/ont/fma/fma82738 |
T267 | 1209-1214 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T268 | 1261-1268 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T269 | 1292-1294 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
T270 | 1319-1330 | Body_part | denotes | neutrophils | http://purl.org/sig/ont/fma/fma62860 |
T271 | 1338-1348 | Body_part | denotes | Peroxisome | http://purl.org/sig/ont/fma/fma63845 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T434 | 1487-1492 | Disease | denotes | Tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T383 | 0-1 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T384 | 61-62 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T385 | 189-197 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
T386 | 252-260 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
T387 | 306-316 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T388 | 324-330 | http://purl.obolibrary.org/obo/CLO_0001869 | denotes | B. (B) |
T389 | 472-474 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | AA |
T390 | 532-536 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T391 | 537-545 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T392 | 581-590 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
T393 | 718-723 | http://purl.obolibrary.org/obo/CLO_0037161 | denotes | (E) N |
T394 | 819-821 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | AA |
T395 | 1033-1059 | http://purl.obolibrary.org/obo/PR_000030035 | denotes | G-protein coupled receptor |
T396 | 1097-1099 | http://purl.obolibrary.org/obo/CLO_0007408 | denotes | LT |
T397 | 1152-1153 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T398 | 1197-1206 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
T399 | 1207-1214 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cells |
T400 | 1292-1294 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
T401 | 1362-1371 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T91966 | 53-58 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T254 | 68-73 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T25762 | 149-158 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
T2516 | 320-322 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
T90528 | 335-340 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T92881 | 384-387 | Chemical | denotes | LTs | http://purl.obolibrary.org/obo/CHEBI_25029 |
T67923 | 435-440 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T52402 | 457-462 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T263 | 472-474 | Chemical | denotes | AA | http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816 |
T265 | 516-520 | Chemical | denotes | PUFA | http://purl.obolibrary.org/obo/CHEBI_26208|http://purl.obolibrary.org/obo/CHEBI_76567 |
T41515 | 600-605 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T49437 | 607-610 | Chemical | denotes | DHA | http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005 |
T8273 | 615-618 | Chemical | denotes | EPA | http://purl.obolibrary.org/obo/CHEBI_28364 |
T273 | 639-642 | Chemical | denotes | CYP | http://purl.obolibrary.org/obo/CHEBI_38559 |
T15459 | 726-731 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
T98235 | 764-768 | Chemical | denotes | SPMs | http://purl.obolibrary.org/obo/CHEBI_140399 |
T61651 | 819-821 | Chemical | denotes | AA | http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816 |
T10468 | 823-839 | Chemical | denotes | Arachidonic acid | http://purl.obolibrary.org/obo/CHEBI_15843 |
T33326 | 835-839 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T93741 | 841-844 | Chemical | denotes | CCL | http://purl.obolibrary.org/obo/CHEBI_3478 |
T49022 | 856-862 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
T32999 | 885-888 | Chemical | denotes | CYP | http://purl.obolibrary.org/obo/CHEBI_38559 |
T44466 | 890-900 | Chemical | denotes | Cytochrome | http://purl.obolibrary.org/obo/CHEBI_4056 |
T12742 | 907-910 | Chemical | denotes | DHA | http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005 |
T92319 | 912-932 | Chemical | denotes | Docosahexaenoic acid | http://purl.obolibrary.org/obo/CHEBI_28125 |
T3064 | 928-932 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T14197 | 939-965 | Chemical | denotes | Epoxydocosapentaenoic acid | http://purl.obolibrary.org/obo/CHEBI_72654 |
T66732 | 961-965 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T292 | 967-970 | Chemical | denotes | EEQ | http://purl.obolibrary.org/obo/CHEBI_144559|http://purl.obolibrary.org/obo/CHEBI_72852 |
T45166 | 972-998 | Chemical | denotes | Epoxyeicosatetraenoic acid | http://purl.obolibrary.org/obo/CHEBI_72852 |
T89769 | 994-998 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T46951 | 1000-1003 | Chemical | denotes | EPA | http://purl.obolibrary.org/obo/CHEBI_28364 |
T32094 | 1005-1026 | Chemical | denotes | Eicosapentaenoic acid | http://purl.obolibrary.org/obo/CHEBI_28364 |
T89321 | 1022-1026 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T33506 | 1028-1031 | Chemical | denotes | GRP | http://purl.obolibrary.org/obo/CHEBI_144473|http://purl.obolibrary.org/obo/CHEBI_80328 |
T56126 | 1035-1042 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T51846 | 1061-1063 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T77398 | 1097-1099 | Chemical | denotes | LT | http://purl.obolibrary.org/obo/CHEBI_73589 |
T305 | 1101-1112 | Chemical | denotes | Leukotriene | http://purl.obolibrary.org/obo/CHEBI_25029 |
T306 | 1114-1118 | Chemical | denotes | PUFA | http://purl.obolibrary.org/obo/CHEBI_26208|http://purl.obolibrary.org/obo/CHEBI_76567 |
T47314 | 1125-1147 | Chemical | denotes | unsaturated fatty acid | http://purl.obolibrary.org/obo/CHEBI_27208 |
T64064 | 1137-1147 | Chemical | denotes | fatty acid | http://purl.obolibrary.org/obo/CHEBI_35366 |
T11513 | 1143-1147 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T26774 | 1149-1151 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
T12903 | 1261-1268 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T14656 | 1382-1385 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
T89630 | 1387-1410 | Chemical | denotes | Reactive oxygen species | http://purl.obolibrary.org/obo/CHEBI_26523 |
T21274 | 1396-1402 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T1686 | 1412-1416 | Chemical | denotes | SPMs | http://purl.obolibrary.org/obo/CHEBI_140399 |
T80333 | 1418-1453 | Chemical | denotes | Specialized pro-resolving mediators | http://purl.obolibrary.org/obo/CHEBI_140399 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T119 | 160-197 | http://purl.obolibrary.org/obo/GO_1900226 | denotes | inhibit NLRP3 inflammasomes, activate |
T120 | 168-197 | http://purl.obolibrary.org/obo/GO_0044546 | denotes | NLRP3 inflammasomes, activate |
T121 | 216-237 | http://purl.obolibrary.org/obo/GO_0000981 | denotes | transcription factors |
T122 | 216-229 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T123 | 489-510 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
T124 | 581-590 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T125 | 890-900 | http://purl.obolibrary.org/obo/GO_0045158 | denotes | Cytochrome |
T126 | 890-900 | http://purl.obolibrary.org/obo/GO_0045157 | denotes | Cytochrome |
T127 | 890-900 | http://purl.obolibrary.org/obo/GO_0045156 | denotes | Cytochrome |
T128 | 890-900 | http://purl.obolibrary.org/obo/GO_0008121 | denotes | Cytochrome |
T129 | 1338-1361 | http://purl.obolibrary.org/obo/GO_0016559 | denotes | Peroxisome proliferator |
T130 | 1493-1501 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T131 | 1493-1501 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T132 | 1493-1501 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T133 | 1493-1501 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T480 | 512-818 | Sentence | denotes | N-3 PUFA will alter cell membrane composition, fluidity and mediated signaling. (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. |
T481 | 819-1511 | Sentence | denotes | AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid; GRP, G-protein coupled receptor; IL, Interleukin; LOX, Lipoxygenase; LT, Leukotriene; PUFA, Poly unsaturated fatty acid; NFκB, Nuclear factor kappa-light-chain enhancer activated B-cells; NLRP3, NACHT, LRR and PYD domains-containing protein 3; PLA2, Phospholipase A2; PMN, Polymorphonuclear neutrophils; PPAR, Peroxisome proliferator-activated receptor; ROS, Reactive oxygen species; SPMs, Specialized pro-resolving mediators; TLR, Toll like receptor; TNF-α, Tumor necrosis factor-α. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T205 | 1487-1492 | Phenotype | denotes | Tumor | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1931 | 168-173 | Gene | denotes | NLRP3 | Gene:114548 |
1932 | 239-244 | Gene | denotes | PPARα | Gene:5465 |
1933 | 261-267 | Gene | denotes | GPR120 | Gene:338557 |
1934 | 292-296 | Gene | denotes | TLR4 | Gene:7099 |
1935 | 320-325 | Gene | denotes | NF-κB | Gene:4790 |
1936 | 885-888 | Gene | denotes | CYP | Gene:4051 |
1937 | 890-905 | Gene | denotes | Cytochrome P450 | Gene:4051 |
1938 | 1028-1031 | Gene | denotes | GRP | Gene:2922 |
1939 | 1114-1118 | Gene | denotes | PUFA | Gene:9933 |
1940 | 1216-1221 | Gene | denotes | NLRP3 | Gene:114548 |
1941 | 1223-1270 | Gene | denotes | NACHT, LRR and PYD domains-containing protein 3 | Gene:114548 |
1942 | 1272-1276 | Gene | denotes | PLA2 | Gene:5320 |
1943 | 1278-1294 | Gene | denotes | Phospholipase A2 | Gene:5319 |
1944 | 1332-1336 | Gene | denotes | PPAR | Gene:5465 |
1945 | 1480-1485 | Gene | denotes | TNF-α | Gene:7124 |
1946 | 1487-1510 | Gene | denotes | Tumor necrosis factor-α | Gene:7124 |
1947 | 516-520 | Gene | denotes | PUFA | Gene:9933 |
1948 | 639-642 | Gene | denotes | CYP | Gene:4051 |
1949 | 431-433 | Chemical | denotes | N- | MESH:D009584 |
1950 | 596-605 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
1951 | 607-610 | Chemical | denotes | DHA | MESH:D004281 |
1952 | 615-618 | Chemical | denotes | EPA | MESH:D015118 |
1953 | 722-731 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |