PMC:7534795 / 64417-64935
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T259 | 121-130 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T260 | 132-142 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T383 | 7-8 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T384 | 68-69 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T385 | 196-204 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
| T386 | 259-267 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
| T387 | 313-323 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T388 | 331-337 | http://purl.obolibrary.org/obo/CLO_0001869 | denotes | B. (B) |
| T389 | 479-481 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | AA |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T91966 | 60-65 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T254 | 75-80 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T25762 | 156-165 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T2516 | 327-329 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
| T90528 | 342-347 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T92881 | 391-394 | Chemical | denotes | LTs | http://purl.obolibrary.org/obo/CHEBI_25029 |
| T67923 | 442-447 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T52402 | 464-469 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T263 | 479-481 | Chemical | denotes | AA | http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T119 | 167-204 | http://purl.obolibrary.org/obo/GO_1900226 | denotes | inhibit NLRP3 inflammasomes, activate |
| T120 | 175-204 | http://purl.obolibrary.org/obo/GO_0044546 | denotes | NLRP3 inflammasomes, activate |
| T121 | 223-244 | http://purl.obolibrary.org/obo/GO_0000981 | denotes | transcription factors |
| T122 | 223-236 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T123 | 496-517 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T479 | 0-518 | Sentence | denotes | Fig. 3 A summary of the anti-inflammatory mechanisms of n-3 PUFAs. (A) N-3 PUFAs can regulate expression of inflammatory cytokines, chemokines and adhesion molecules, inhibit NLRP3 inflammasomes, activate anti-inflammatory transcription factors (PPARα/γ) and activate GPR120 receptors which inhibit TLR4-mediated activation of NF-κB. (B) N-3 PUFAs are metabolized by COX/5-LOX into 5-series LTs which exert anti-inflammatory effects. (C) N-3 PUFAs can replace n-6 PUFAs, such as AA, altering the inflammatory response. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1931 | 175-180 | Gene | denotes | NLRP3 | Gene:114548 |
| 1932 | 246-251 | Gene | denotes | PPARα | Gene:5465 |
| 1933 | 268-274 | Gene | denotes | GPR120 | Gene:338557 |
| 1934 | 299-303 | Gene | denotes | TLR4 | Gene:7099 |
| 1935 | 327-332 | Gene | denotes | NF-κB | Gene:4790 |
| 1949 | 438-440 | Chemical | denotes | N- | MESH:D009584 |