PMC:7534795 / 40093-40501 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T188","span":{"begin":39,"end":47},"obj":"Body_part"},{"id":"T189","span":{"begin":69,"end":74},"obj":"Body_part"}],"attributes":[{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma67498"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T68","span":{"begin":69,"end":74},"obj":"Body_part"}],"attributes":[{"id":"A68","pred":"uberon_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T318","span":{"begin":326,"end":333},"obj":"Disease"}],"attributes":[{"id":"A318","pred":"mondo_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/MONDO_0005047"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T266","span":{"begin":69,"end":74},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T267","span":{"begin":391,"end":393},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T268","span":{"begin":391,"end":393},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T303","span":{"begin":12,"end":14},"obj":"Chemical"},{"id":"T304","span":{"begin":15,"end":24},"obj":"Chemical"},{"id":"T307","span":{"begin":15,"end":22},"obj":"Chemical"},{"id":"T308","span":{"begin":182,"end":191},"obj":"Chemical"},{"id":"T309","span":{"begin":182,"end":189},"obj":"Chemical"},{"id":"T310","span":{"begin":266,"end":275},"obj":"Chemical"},{"id":"T311","span":{"begin":266,"end":273},"obj":"Chemical"},{"id":"T312","span":{"begin":334,"end":339},"obj":"Chemical"},{"id":"T313","span":{"begin":391,"end":393},"obj":"Chemical"}],"attributes":[{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_74327"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A305","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_29073"},{"id":"A306","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_38290"},{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A310","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A311","pred":"chebi_id","subj":"T311","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A312","pred":"chebi_id","subj":"T312","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A313","pred":"chebi_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-sentences","denotations":[{"id":"T292","span":{"begin":0,"end":153},"obj":"Sentence"},{"id":"T293","span":{"begin":154,"end":164},"obj":"Sentence"},{"id":"T294","span":{"begin":165,"end":210},"obj":"Sentence"},{"id":"T295","span":{"begin":211,"end":408},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T152","span":{"begin":39,"end":53},"obj":"Phenotype"}],"attributes":[{"id":"A152","pred":"hp_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1317","span":{"begin":182,"end":191},"obj":"Chemical"},{"id":"1318","span":{"begin":266,"end":275},"obj":"Chemical"},{"id":"1319","span":{"begin":334,"end":339},"obj":"Chemical"},{"id":"1338","span":{"begin":69,"end":86},"obj":"Disease"}],"attributes":[{"id":"A1317","pred":"tao:has_database_id","subj":"1317","obj":"MESH:D001205"},{"id":"A1318","pred":"tao:has_database_id","subj":"1318","obj":"MESH:D001205"},{"id":"A1319","pred":"tao:has_database_id","subj":"1319","obj":"MESH:D014867"},{"id":"A1338","pred":"tao:has_database_id","subj":"1338","obj":"MESH:D009102"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"• High dose IV Vitamin C to ameliorate cytokine storm and associated organ dysfunction • Prospective placebo controlled randomized controlled trial (RCT)\n• N = 308\n• High dose i.v. vitamin C (HIVC) vs. placebo\n• Primary outcome of ventilator-free days • 12 g/50 ml vitamin C infusion 12 ml/h twice daily for 7 days vs. 50 ml sterile water for injection infused at 12 ml/h (Liu, Zhu, Zhang, Li, \u0026 Peng, 2020)"}