PMC:7534795 / 16141-16568 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7534795","sourcedb":"PMC","sourceid":"7534795","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7534795","text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T18588","span":{"begin":7,"end":11},"obj":"Body_part"},{"id":"T98401","span":{"begin":65,"end":69},"obj":"Body_part"},{"id":"T41658","span":{"begin":151,"end":156},"obj":"Body_part"},{"id":"T3586","span":{"begin":165,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A89911","pred":"fma_id","subj":"T18588","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A63637","pred":"fma_id","subj":"T98401","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A61401","pred":"fma_id","subj":"T41658","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A43859","pred":"fma_id","subj":"T3586","obj":"http://purl.org/sig/ont/fma/fma7195"},{"subj":"T18588","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T98401","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T41658","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T3586","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":151,"end":156},"obj":"Body_part"},{"id":"T28","span":{"begin":165,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T157","span":{"begin":246,"end":254},"obj":"Disease"},{"id":"T158","span":{"begin":318,"end":326},"obj":"Disease"},{"id":"T159","span":{"begin":383,"end":391},"obj":"Disease"}],"attributes":[{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A159","pred":"mondo_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T159","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T81427","span":{"begin":7,"end":11},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T43208","span":{"begin":65,"end":69},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T64659","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T27439","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T19348","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T68420","span":{"begin":151,"end":156},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T90334","span":{"begin":165,"end":169},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T21446","span":{"begin":165,"end":169},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"attributes":[{"subj":"T81427","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T43208","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T64659","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T27439","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T19348","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T68420","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T90334","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T21446","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T122","span":{"begin":22,"end":33},"obj":"Chemical"}],"attributes":[{"id":"A122","pred":"chebi_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"subj":"T122","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"2_test","denotations":[{"id":"33031856-32264791-84038838","span":{"begin":94,"end":98},"obj":"32264791"},{"id":"33031856-27081112-84038839","span":{"begin":201,"end":205},"obj":"27081112"}],"attributes":[{"subj":"33031856-32264791-84038838","pred":"source","obj":"2_test"},{"subj":"33031856-27081112-84038839","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"561","span":{"begin":22,"end":53},"obj":"Gene"},{"id":"562","span":{"begin":55,"end":59},"obj":"Gene"},{"id":"563","span":{"begin":114,"end":118},"obj":"Gene"},{"id":"564","span":{"begin":260,"end":264},"obj":"Gene"},{"id":"577","span":{"begin":246,"end":256},"obj":"Species"},{"id":"578","span":{"begin":318,"end":326},"obj":"Species"},{"id":"579","span":{"begin":383,"end":393},"obj":"Species"}],"attributes":[{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"Gene:59272"},{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"Gene:59272"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"Gene:59272"},{"id":"A564","pred":"tao:has_database_id","subj":"564","obj":"Gene:59272"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"Tax:2697049"},{"id":"A578","pred":"tao:has_database_id","subj":"578","obj":"Tax:694009"},{"id":"A579","pred":"tao:has_database_id","subj":"579","obj":"Tax:2697049"},{"subj":"561","pred":"source","obj":"LitCovid-PubTator"},{"subj":"562","pred":"source","obj":"LitCovid-PubTator"},{"subj":"563","pred":"source","obj":"LitCovid-PubTator"},{"subj":"564","pred":"source","obj":"LitCovid-PubTator"},{"subj":"577","pred":"source","obj":"LitCovid-PubTator"},{"subj":"578","pred":"source","obj":"LitCovid-PubTator"},{"subj":"579","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#d193ec","default":true},{"id":"LitCovid-PD-UBERON","color":"#93ecb7"},{"id":"LitCovid-PD-MONDO","color":"#ec9d93"},{"id":"LitCovid-PD-CLO","color":"#93a2ec"},{"id":"LitCovid-PD-CHEBI","color":"#bcec93"},{"id":"2_test","color":"#ec93d6"},{"id":"LitCovid-PubTator","color":"#93ece7"}]}]}}