PMC:7534795 / 16141-16568 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T18588","span":{"begin":7,"end":11},"obj":"Body_part"},{"id":"T98401","span":{"begin":65,"end":69},"obj":"Body_part"},{"id":"T41658","span":{"begin":151,"end":156},"obj":"Body_part"},{"id":"T3586","span":{"begin":165,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A89911","pred":"fma_id","subj":"T18588","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A63637","pred":"fma_id","subj":"T98401","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A61401","pred":"fma_id","subj":"T41658","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A43859","pred":"fma_id","subj":"T3586","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":151,"end":156},"obj":"Body_part"},{"id":"T28","span":{"begin":165,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T157","span":{"begin":246,"end":254},"obj":"Disease"},{"id":"T158","span":{"begin":318,"end":326},"obj":"Disease"},{"id":"T159","span":{"begin":383,"end":391},"obj":"Disease"}],"attributes":[{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A159","pred":"mondo_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T81427","span":{"begin":7,"end":11},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T43208","span":{"begin":65,"end":69},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T64659","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T27439","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T19348","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T68420","span":{"begin":151,"end":156},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T90334","span":{"begin":165,"end":169},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T21446","span":{"begin":165,"end":169},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}

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{"project":"2_test","denotations":[{"id":"33031856-32264791-84038838","span":{"begin":94,"end":98},"obj":"32264791"},{"id":"33031856-27081112-84038839","span":{"begin":201,"end":205},"obj":"27081112"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}

{"project":"LitCovid-PubTator","denotations":[{"id":"561","span":{"begin":22,"end":53},"obj":"Gene"},{"id":"562","span":{"begin":55,"end":59},"obj":"Gene"},{"id":"563","span":{"begin":114,"end":118},"obj":"Gene"},{"id":"564","span":{"begin":260,"end":264},"obj":"Gene"},{"id":"577","span":{"begin":246,"end":256},"obj":"Species"},{"id":"578","span":{"begin":318,"end":326},"obj":"Species"},{"id":"579","span":{"begin":383,"end":393},"obj":"Species"}],"attributes":[{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"Gene:59272"},{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"Gene:59272"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"Gene:59272"},{"id":"A564","pred":"tao:has_database_id","subj":"564","obj":"Gene:59272"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"Tax:2697049"},{"id":"A578","pred":"tao:has_database_id","subj":"578","obj":"Tax:694009"},{"id":"A579","pred":"tao:has_database_id","subj":"579","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"l host-cell receptor, angiotensin-converting enzyme 2 (ACE2) for cell entry (Gheblawi et al., 2020). Importantly, ACE2 is highly expressed in both the heart and the lung (Patel, Zhong, Grant, \u0026 Oudit, 2016) and evidence indicates the affinity of SARS-CoV-2 to ACE2 is approximately 10- to 20-fold higher than that for SARS-CoV which may account for both the greater pathogenicity of SARS-CoV-2 and the rapid spread (Gheblawi et"}