PMC:7532482 / 13378-14091 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7532482","sourcedb":"PMC","sourceid":"7532482","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7532482","text":"The ingredient-target network of SFJDC was constructed using the screened ingredients and their targets as shown in Figure 3. The network contained 117 nodes and 419 edges which indicated the compound-target genes interaction. A median of 110 candidate compouds was 5 degrees which indicating that most compounds of SFJDC were affected by multiple target genes. The top three effective ingredient according were Wogonin, licochalcone a and acacetin. Wogonin, licochalcone a and acacetin have 42, 30 and 23 target genes, respectively. And the OB of Wogonin, licochalcone a and acacetin were 30.68, 40.79 and 34.97%, respectively. Hence, they might be the crucial effective compounds of SFJDC according the 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