PMC:7519301 / 46832-47592 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7519301","sourcedb":"PMC","sourceid":"7519301","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7519301","text":"T Cell Immunogenicity Index.\nFor each site in a predicted epitope, the immunogenicity index was defined as the sum of the frequency of the HLA alleles or haplotypes restricting the corresponding epitope (multiple epitopes can be predicted at a given site in a protein). Total frequencies from CIWD 3.0 were used as the frequencies of the corresponding MHC class I HLA alleles (HLA-A, HLA-B, and HLA-C), and the global frequencies from http://17ihiw.org/17th-ihiw-ngs-hla-data/ were used as the frequencies of the corresponding MHC class II HLA alleles or haplotypes (HLA-DQB1, HLA-DPA1-DPB1, and HLA-DQA1-DPB). This procedure was repeated using the frequencies of MHC alleles or haplotypes in different subpopulations listed in the above HLA frequency 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