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PMC:7519301 / 29126-30373 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T101 319-323 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T102 628-632 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T150 23-31 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T151 23-27 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T152 504-512 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T153 504-508 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T154 610-618 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T155 610-614 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T156 661-669 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T157 661-665 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T235 100-103 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T236 136-143 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T237 213-214 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T238 319-323 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T239 522-528 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T240 558-559 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T241 628-632 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T242 864-871 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T243 907-908 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
430 699-700 Gene denotes S Gene:43740568
431 23-33 Species denotes SARS-CoV-2 Tax:2697049
432 504-514 Species denotes SARS-CoV-2 Tax:2697049
433 522-528 Species denotes humans Tax:9606
434 610-618 Species denotes SARS-CoV Tax:694009
435 661-671 Species denotes SARS-CoV-2 Tax:2697049
436 1144-1148 Species denotes ncov Tax:2697049
437 173-180 Disease denotes fitness MESH:D012640
438 1029-1034 Mutation denotes D614G p.D614G
439 885-890 Mutation denotes D614G p.D614G
440 693-698 Mutation denotes D614G p.D614G
441 353-358 Mutation denotes D614G p.D614G
442 149-154 Mutation denotes D614G p.D614G
443 69-74 Mutation denotes D614G p.D614G

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T3 827-839 http://purl.obolibrary.org/obo/GO_0000003 denotes reproduction
T4 1099-1111 http://purl.obolibrary.org/obo/GO_0000003 denotes reproduction

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T179 0-186 Sentence denotes In the context of rare SARS-CoV-2 mutations, the rapid spread of the D614G mutation is singular and has led authors to hypothesize that viruses with D614G may have enhanced fitness (24).
T180 187-367 Sentence denotes The strongest evidence of a biological effect for this mutation comes from recent reports of an increase in in vitro infectivity or cell entry for pseudoviruses with D614G (25–28).
T181 368-596 Sentence denotes Additional work is needed to evaluate whether the increase in infectivity in vitro translates to increased transmissibility (spread) of SARS-CoV-2 across humans, as there is not necessarily a linear relationship between the two.
T182 597-716 Sentence denotes For example, SARS-CoV mediates cell entry more efficiently than SARS-CoV-2 (with or without the D614G S mutation) (26).
T183 717-900 Sentence denotes Hence, it would be important to understand whether, controlling for epidemiological factors, there are higher reproduction numbers associated with viruses carrying the D614G mutation.
T184 901-1247 Sentence denotes While a preliminary comparison of the lineages with either D or G in Washington State did not indicate an obvious advantage for D614G mutants, as they found similar maximal values for the effective reproduction number (https://github.com/blab/ncov-wa-phylodynamics), additional comparisons in different geographic locations should be informative.

2_test

Id Subject Object Predicate Lexical cue
32868447-32697968-132542407 182-184 32697968 denotes 24