PMC:7473478 / 2578-3760
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T28 | 168-174 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T29 | 185-189 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T30 | 226-234 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
| T31 | 269-279 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
| T32 | 293-300 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T33 | 321-324 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T34 | 510-515 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T35 | 520-528 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T36 | 523-528 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T37 | 591-596 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T38 | 612-625 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T39 | 650-664 | Body_part | denotes | helper T cells | http://purl.org/sig/ont/fma/fma70572 |
| T40 | 659-664 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T41 | 690-695 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T42 | 701-719 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T43 | 714-719 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T44 | 833-851 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T45 | 846-851 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T46 | 984-989 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T47 | 1013-1018 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T48 | 1091-1096 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T4 | 612-625 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T21 | 112-120 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T22 | 152-160 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 551-559 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T24 | 752-760 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 900-912 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T26 | 1171-1179 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T25 | 168-174 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T26 | 206-210 | http://purl.obolibrary.org/obo/CLO_0053704 | denotes | IL-8 |
| T27 | 226-234 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
| T28 | 252-259 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T29 | 319-324 | http://purl.obolibrary.org/obo/PR_000005932 | denotes | G-CSF |
| T30 | 508-515 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T31 | 520-528 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T32 | 591-596 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T33 | 612-625 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T34 | 650-664 | http://purl.obolibrary.org/obo/CL_0000912 | denotes | helper T cells |
| T35 | 688-695 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T36 | 701-719 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T37 | 833-851 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T38 | 914-916 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T39 | 935-936 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T40 | 976-989 | http://purl.obolibrary.org/obo/CL_0000898 | denotes | naïve T cells |
| T41 | 1011-1018 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T42 | 1091-1096 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T43 | 1104-1105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T3 | 185-187 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T5 | 192-194 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T7 | 200-202 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T9 | 206-208 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T11 | 212-214 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T13 | 252-259 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T14 | 261-264 | Chemical | denotes | MCP | http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099 |
| T16 | 293-300 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 68 | 185-190 | Gene | denotes | IL-1β | Gene:3552 |
| 69 | 192-198 | Gene | denotes | IL-1RA | Gene:3557 |
| 70 | 200-204 | Gene | denotes | IL-7 | Gene:3574 |
| 71 | 206-210 | Gene | denotes | IL-8 | Gene:3576 |
| 72 | 212-217 | Gene | denotes | IL-10 | Gene:3586 |
| 73 | 219-224 | Gene | denotes | IFN-γ | Gene:3458 |
| 74 | 226-267 | Gene | denotes | monocyte chemoattrac-tant peptide (MCP)-1 | Gene:6347 |
| 75 | 269-309 | Gene | denotes | macrophage inflammatory protein (MIP)-1A | Gene:6348 |
| 76 | 311-317 | Gene | denotes | MIP-1B | Gene:6351 |
| 77 | 319-324 | Gene | denotes | G-CSF | Gene:1440 |
| 78 | 330-335 | Gene | denotes | TNF-α | Gene:7124 |
| 79 | 1106-1110 | Gene | denotes | plau | Gene:5328 |
| 80 | 129-137 | Species | denotes | patients | Tax:9606 |
| 81 | 152-162 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 82 | 429-437 | Species | denotes | patients | Tax:9606 |
| 83 | 560-568 | Species | denotes | patients | Tax:9606 |
| 84 | 738-746 | Species | denotes | patients | Tax:9606 |
| 85 | 1043-1051 | Species | denotes | patients | Tax:9606 |
| 86 | 1171-1181 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 87 | 112-120 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 88 | 138-146 | Disease | denotes | infected | MESH:D007239 |
| 89 | 551-559 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 90 | 752-760 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 91 | 900-912 | Disease | denotes | inflammation | MESH:D007249 |
| 92 | 1004-1012 | Disease | denotes | memory T | MESH:D008569 |
| 93 | 1034-1042 | Disease | denotes | infected | MESH:D007239 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5 | 192-198 | http://purl.obolibrary.org/obo/GO_0005152 | denotes | IL-1RA |
| T6 | 900-912 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T7 | 1004-1010 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T8 | 1084-1090 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T22 | 0-125 | Sentence | denotes | The dynamic equilibrium maintained by innate and adaptive immunity is essential for impeding the progression of COVID-19 (7). |
| T23 | 126-378 | Sentence | denotes | In patients infected with SARS-CoV-2, the plasma levels of IL-1β, IL-1RA, IL-7, IL-8, IL-10, IFN-γ, monocyte chemoattrac-tant peptide (MCP)-1, macrophage inflammatory protein (MIP)-1A, MIP-1B, G-CSF, and TNF-α are significantly higher than in controls. |
| T24 | 379-468 | Sentence | denotes | The levels of these factors are also increased in patients who were admitted to ICUs (8). |
| T25 | 469-573 | Sentence | denotes | Similarly, reductions in the levels of T cells and NK cells have been observed in COVID-19 patients (9). |
| T26 | 574-631 | Sentence | denotes | The loss of such cells can impair the immune system (10). |
| T27 | 632-812 | Sentence | denotes | The levels of the helper T cells, cytotoxic suppressive T cells, and regulatory T cells are much lower in patients with COVID-19 than in their healthy and less severe counterparts. |
| T28 | 813-918 | Sentence | denotes | The decrease in the regulatory T cells may hamper their ability to inhibit the chronic inflammation (11). |
| T29 | 919-1057 | Sentence | denotes | Interes-tingly, a remarkable increase is observed in the naïve T cells, where as the memory T cells are reduced in infected patients (10). |
| T30 | 1058-1182 | Sentence | denotes | The reduced expression of memory cells may be a plau-sible explanation for the increased rates of reinfection by SARS-CoV-2. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32731913-31981224-8028458 | 122-123 | 31981224 | denotes | 7 |
| 32731913-32161940-8028459 | 465-466 | 32161940 | denotes | 8 |
| 32731913-32299202-8028460 | 627-629 | 32299202 | denotes | 10 |
| 32731913-20559327-8028461 | 914-916 | 20559327 | denotes | 11 |
| 32731913-32299202-8028462 | 1053-1055 | 32299202 | denotes | 10 |