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PMC:7463108 / 96122-96886 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T904 15-18 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T905 107-110 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T906 221-225 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T907 267-278 Body_part denotes hippocampus http://purl.org/sig/ont/fma/fma275020
T908 283-291 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T909 376-384 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T910 394-398 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T911 413-424 Body_part denotes hippocampus http://purl.org/sig/ont/fma/fma275020
T912 509-512 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T913 624-629 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T914 635-639 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T915 682-685 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T916 745-749 Body_part denotes HAND http://purl.org/sig/ont/fma/fma9712

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T174 107-110 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T175 283-291 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T176 376-384 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T177 624-629 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T963 54-61 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T964 107-110 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T965 107-110 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T966 107-110 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T967 590-598 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T968 622-623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T969 624-629 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T970 624-629 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T971 635-644 http://purl.obolibrary.org/obo/CL_0000000 denotes cell-type

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T84666 54-61 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T81260 590-598 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3372 216-220 Gene denotes PDYN Gene:18610
3373 295-298 Gene denotes Tat Gene:234724
3374 316-320 Gene denotes POMC Gene:18976
3375 355-358 Gene denotes Tat Gene:234724
3376 389-393 Gene denotes PENK Gene:18619
3377 466-469 Gene denotes Tat Gene:234724
3378 148-151 Gene denotes tat Gene:6898
3379 19-22 Gene denotes Tat Gene:6898
3380 310-314 Species denotes mice Tax:10090
3381 682-687 Species denotes HIV-1 Tax:11676
3382 15-18 Species denotes HIV Tax:12721
3383 509-512 Species denotes HIV Tax:12721

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1228 0-188 Sentence denotes The effects of HIV Tat on expression levels of opioid peptide and receptor levels depend on the individual CNS region involved as well as levels of tat transgene expression (Fitting et al.
T1229 189-196 Sentence denotes 2010b).
T1230 197-494 Sentence denotes For example, while PDYN mRNA levels were significantly reduced in the hippocampus and striatum of Tat-expressing mice, POMC was only significantly reduced by Tat induction in the striatum and PENK mRNA levels in the hippocampus were affected by chronic (but not acute) Tat exposure (Fitting et al.
T1231 495-502 Sentence denotes 2010b).
T1232 503-661 Sentence denotes Thus, HIV may alter the endogenous opioid system by modifying the expression of opioid peptides and their receptors in a brain- and cell-type specific manner.
T1233 662-764 Sentence denotes The consequences of HIV-1-dependent alterations in the endogenous opioid system to HAND are uncertain.