PMC:7463108 / 91701-92004
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T870 | 86-89 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T925 | 164-173 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T926 | 231-232 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 3154 | 68-72 | Gene | denotes | CCR5 | Gene:1234 |
| 3155 | 182-185 | Gene | denotes | MOR | Gene:4988 |
| 3156 | 200-204 | Gene | denotes | CCR5 | Gene:1234 |
| 3157 | 218-221 | Gene | denotes | MOR | Gene:4988 |
| 3158 | 233-237 | Gene | denotes | BDNF | Gene:627 |
| 3168 | 86-91 | Species | denotes | HIV-1 | Tax:11676 |
| 3200 | 96-113 | Disease | denotes | opiate neurotoxic | MESH:D020258 |
| 3201 | 137-152 | Disease | denotes | CCR5 deficiency | MESH:D007153 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T175 | 164-173 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T176 | 274-291 | http://purl.obolibrary.org/obo/GO_0043524 | denotes | neuronal survival |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1185 | 0-303 | Sentence | denotes | Overall, the results in c-h suggest (1) an important role for glial CCR5 in mediating HIV-1 and opiate neurotoxic interactions, (2) that CCR5 deficiency influences signaling through MOR, and (3) that CCR5 (and perhaps MOR) act via a BDNF intermediary to promote or obstruct neuronal survival (Kim et al. |