PMC:7463108 / 17970-18263 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T106","span":{"begin":10,"end":13},"obj":"Body_part"},{"id":"T107","span":{"begin":19,"end":22},"obj":"Body_part"},{"id":"T108","span":{"begin":86,"end":91},"obj":"Body_part"},{"id":"T109","span":{"begin":111,"end":117},"obj":"Body_part"},{"id":"T110","span":{"begin":118,"end":127},"obj":"Body_part"},{"id":"T111","span":{"begin":128,"end":131},"obj":"Body_part"},{"id":"T112","span":{"begin":212,"end":218},"obj":"Body_part"},{"id":"T113","span":{"begin":244,"end":247},"obj":"Body_part"}],"attributes":[{"id":"A106","pred":"fma_id","subj":"T106","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A107","pred":"fma_id","subj":"T107","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A108","pred":"fma_id","subj":"T108","obj":"http://purl.org/sig/ont/fma/fma50801"},{"id":"A109","pred":"fma_id","subj":"T109","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A112","pred":"fma_id","subj":"T112","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A113","pred":"fma_id","subj":"T113","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T34","span":{"begin":86,"end":91},"obj":"Body_part"}],"attributes":[{"id":"A34","pred":"uberon_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T40","span":{"begin":27,"end":31},"obj":"Disease"},{"id":"T41","span":{"begin":178,"end":180},"obj":"Disease"}],"attributes":[{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0020689"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0019903"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T134","span":{"begin":4,"end":8},"obj":"http://purl.obolibrary.org/obo/PR_000002064"},{"id":"T135","span":{"begin":63,"end":67},"obj":"http://purl.obolibrary.org/obo/PR_000002064"},{"id":"T136","span":{"begin":68,"end":73},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T137","span":{"begin":86,"end":91},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T138","span":{"begin":86,"end":91},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T139","span":{"begin":111,"end":117},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T140","span":{"begin":205,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0008697"},{"id":"T141","span":{"begin":205,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052381"},{"id":"T142","span":{"begin":212,"end":218},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T143","span":{"begin":219,"end":224},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T70","span":{"begin":142,"end":149},"obj":"Chemical"},{"id":"T72","span":{"begin":151,"end":159},"obj":"Chemical"},{"id":"T73","span":{"begin":161,"end":169},"obj":"Chemical"},{"id":"T75","span":{"begin":267,"end":273},"obj":"Chemical"}],"attributes":[{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_16714"},{"id":"A71","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_57871"},{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_119915"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A74","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A75","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_27808"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-PubTator","denotations":[{"id":"530","span":{"begin":4,"end":8},"obj":"Gene"},{"id":"531","span":{"begin":63,"end":67},"obj":"Gene"},{"id":"532","span":{"begin":193,"end":198},"obj":"Gene"},{"id":"533","span":{"begin":282,"end":288},"obj":"Gene"},{"id":"614","span":{"begin":68,"end":73},"obj":"Species"},{"id":"615","span":{"begin":219,"end":224},"obj":"Species"},{"id":"681","span":{"begin":19,"end":22},"obj":"Species"},{"id":"762","span":{"begin":128,"end":140},"obj":"Disease"},{"id":"763","span":{"begin":244,"end":251},"obj":"Disease"}],"attributes":[{"id":"A530","pred":"tao:has_database_id","subj":"530","obj":"Gene:968"},{"id":"A531","pred":"tao:has_database_id","subj":"531","obj":"Gene:968"},{"id":"A532","pred":"tao:has_database_id","subj":"532","obj":"Gene:7124"},{"id":"A533","pred":"tao:has_database_id","subj":"533","obj":"Gene:6348"},{"id":"A614","pred":"tao:has_database_id","subj":"614","obj":"Tax:9606"},{"id":"A615","pred":"tao:has_database_id","subj":"615","obj":"Tax:9606"},{"id":"A681","pred":"tao:has_database_id","subj":"681","obj":"Tax:12721"},{"id":"A762","pred":"tao:has_database_id","subj":"762","obj":"MESH:D015658"},{"id":"A763","pred":"tao:has_database_id","subj":"763","obj":"MESH:D015658"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"LitCovid-sentences","denotations":[{"id":"T251","span":{"begin":41,"end":104},"obj":"Sentence"},{"id":"T252","span":{"begin":105,"end":110},"obj":"Sentence"},{"id":"T253","span":{"begin":111,"end":237},"obj":"Sentence"},{"id":"T254","span":{"begin":238,"end":243},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}

{"project":"2_test","denotations":[{"id":"32876803-15000697-62957989","span":{"begin":238,"end":242},"obj":"15000697"}],"text":"• ↓ CD68, HLA-D in HIV and HIVE with OUD\n• No effect of IDU on CD68 Human, postmortem brain (Byrd et al. 2012)\nPlasma cytokines HIV cART OUD (codeine, fentanyl, morphine) ↑ sTNF-R2, not sCD14, TNF-α, sTNF-R1, in plasma Human (Ryan et al. 2004)\nHIV ARV naive Reported heroin use • ↓ MIP-1α, MIP"}