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PMC:7461420 / 92463-93481 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T334 19-26 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T335 137-140 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T336 644-660 Body_part denotes neurotransmitter http://purl.org/sig/ont/fma/fma302832
T337 754-757 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T338 903-911 Body_part denotes estrogen http://purl.org/sig/ont/fma/fma83376

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T434 197-201 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T435 810-814 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T436 967-971 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1040 103-113 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1041 425-433 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1042 550-560 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1043 726-733 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T1044 903-920 http://purl.obolibrary.org/obo/PR_000007204 denotes estrogen receptor

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T654 19-26 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T655 38-48 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T656 49-62 Chemical denotes cycloheximide http://purl.obolibrary.org/obo/CHEBI_27641
T657 137-159 Chemical denotes HIV protease inhibitor http://purl.obolibrary.org/obo/CHEBI_35660
T658 141-159 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T660 150-159 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T661 160-169 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T662 235-254 Chemical denotes antidiarrheal agent http://purl.obolibrary.org/obo/CHEBI_55323
T663 255-265 Chemical denotes loperamide http://purl.obolibrary.org/obo/CHEBI_6532
T664 352-360 Chemical denotes alkaloid http://purl.obolibrary.org/obo/CHEBI_22315
T665 392-399 Chemical denotes emetine http://purl.obolibrary.org/obo/CHEBI_4781
T666 415-424 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T667 456-475 Chemical denotes antiparasitic drugs http://purl.obolibrary.org/obo/CHEBI_35442
T668 470-475 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T669 476-487 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T670 489-507 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T671 513-523 Chemical denotes mefloquine http://purl.obolibrary.org/obo/CHEBI_63609
T672 540-549 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T673 590-599 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T674 644-660 Chemical denotes neurotransmitter http://purl.obolibrary.org/obo/CHEBI_25512
T675 661-671 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T676 673-687 Chemical denotes chlorpromazine http://purl.obolibrary.org/obo/CHEBI_3647
T677 692-707 Chemical denotes triflupromazine http://purl.obolibrary.org/obo/CHEBI_9711
T678 754-777 Chemical denotes DNA synthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_59517
T679 754-757 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T680 768-777 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T681 778-789 Chemical denotes gemcitabine http://purl.obolibrary.org/obo/CHEBI_175901
T682 903-911 Chemical denotes estrogen http://purl.obolibrary.org/obo/CHEBI_50114
T683 923-933 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T116 19-37 http://purl.obolibrary.org/obo/GO_0016485 denotes protein‐processing
T117 754-767 http://purl.obolibrary.org/obo/GO_0071897 denotes DNA synthesis
T118 758-767 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2826 903-922 Gene denotes estrogen receptor 1 Gene:2099
2827 127-131 Species denotes CoVs Tax:11118
2828 197-205 Species denotes SARS‐CoV Tax:694009
2829 574-578 Species denotes CoVs Tax:11118
2830 810-818 Species denotes SARS‐CoV Tax:694009
2831 825-833 Species denotes MERS‐CoV Tax:1335626
2832 954-962 Species denotes MERS‐CoV Tax:1335626
2833 967-975 Species denotes SARS‐CoV Tax:694009
2834 221-229 Species denotes MERS‐CoV Tax:1335626
2835 316-320 Species denotes CoVs Tax:11118
2836 442-450 Species denotes MERS‐CoV Tax:1335626
2837 49-62 Chemical denotes cycloheximide MESH:D003513
2838 67-77 Chemical denotes anisomycin MESH:D000841
2839 160-169 Chemical denotes lopinavir MESH:D061466
2840 255-265 Chemical denotes loperamide MESH:D008139
2841 392-399 Chemical denotes emetine MESH:D004640
2842 476-487 Chemical denotes chloroquine MESH:D002738
2843 489-507 Chemical denotes hydroxychloroquine MESH:D006886
2844 513-523 Chemical denotes mefloquine MESH:D015767
2845 601-607 Chemical denotes E‐64‐D
2846 673-687 Chemical denotes chlorpromazine MESH:D002746
2847 692-707 Chemical denotes triflupromazine MESH:D014273
2848 778-789 Chemical denotes gemcitabine MESH:C056507
2849 886-896 Chemical denotes Toremifene MESH:D017312

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T822 0-132 Sentence denotes In particular, the protein‐processing inhibitors cycloheximide and anisomycin showed strong inhibitory activities against both CoVs.
T823 133-230 Sentence denotes The HIV protease inhibitor lopinavir was more effective against SARS‐CoV‐1 than against MERS‐CoV.
T824 231-321 Sentence denotes The antidiarrheal agent loperamide showed moderate inhibitory activitiy against both CoVs.
T825 322-451 Sentence denotes The anti‐protozoal and emetic alkaloid with antibacterial properties, emetine, showed strong antiviral activity against MERS‐CoV.
T826 452-579 Sentence denotes The antiparasitic drugs chloroquine, hydroxychloroquine, and mefloquine showed moderate antiviral activities against both CoVs.
T827 580-632 Sentence denotes Cathepsin inhibitor, E‐64‐D, inhibited both as well.
T828 633-885 Sentence denotes Two of the neurotransmitter inhibitors, chlorpromazine and triflupromazine also blocked both viruses (see Section 2) The DNA synthesis inhibitor gemcitabine was able to inhibit SARS‐CoV‐1 and MERS‐CoV with an EC50 value of 1.2 and 4.9 µM, respectively.
T829 886-1018 Sentence denotes Toremifene is an estrogen receptor 1 antagonist that inhibited both MERS‐CoV and SARS‐CoV‐1 (EC50, 12.9 and 11.97 µM, respectively).