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PMC:7461420 / 63109-63457
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T264 | 220-224 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T297 | 104-108 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T792 | 181-189 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T793 | 208-224 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity in cell |
T794 | 335-337 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T41984 | 14-20 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
T15863 | 90-100 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T76768 | 198-207 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T59369 | 335-337 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1925 | 115-119 | Gene | denotes | Mpro | Gene:8673700 |
1926 | 104-112 | Species | denotes | SARS‐CoV | Tax:694009 |
1927 | 0-20 | Chemical | denotes | Benzotriazole esters |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T548 | 0-120 | Sentence | denotes | Benzotriazole esters (88–91; Figure 26) were discovered as novel nonpeptidic irreversible inhibitors of SARS‐CoV‐1 Mpro. |
T549 | 121-238 | Sentence | denotes | 168 Among them, 91 exhibited the best enzymatic inhibitory activity, but no antiviral activity in cell‐based assays. |
T550 | 239-348 | Sentence | denotes | The covalent binding mode of 91 was confirmed by electrospray ionization mass spectrometry (ESI‐MS) analyses. |