PMC:7461420 / 51206-51446 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7461420","sourcedb":"PMC","sourceid":"7461420","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7461420","text":"Very recently, Dai et al. designed and synthesized two novel peptidomimetic SARS‐CoV‐2 Mpro inhibitors 61 and 62 (Figure 18) which exhibited extremely high inhibitory activity on purified Mpro with IC50 values of 50 and 40 nM, respectively.","tracks":[{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T248","span":{"begin":76,"end":80},"obj":"Disease"}],"attributes":[{"id":"A248","pred":"mondo_id","subj":"T248","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T248","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T648","span":{"begin":121,"end":123},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T649","span":{"begin":141,"end":150},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T650","span":{"begin":167,"end":175},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"attributes":[{"subj":"T648","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T649","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T650","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T71965","span":{"begin":61,"end":75},"obj":"Chemical"},{"id":"T35724","span":{"begin":87,"end":102},"obj":"Chemical"},{"id":"T19702","span":{"begin":92,"end":102},"obj":"Chemical"}],"attributes":[{"id":"A64698","pred":"chebi_id","subj":"T71965","obj":"http://purl.obolibrary.org/obo/CHEBI_63175"},{"id":"A75502","pred":"chebi_id","subj":"T35724","obj":"http://purl.obolibrary.org/obo/CHEBI_147285"},{"id":"A27515","pred":"chebi_id","subj":"T19702","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T71965","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T35724","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T19702","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1544","span":{"begin":87,"end":91},"obj":"Gene"},{"id":"1545","span":{"begin":188,"end":192},"obj":"Gene"},{"id":"1547","span":{"begin":76,"end":86},"obj":"Species"}],"attributes":[{"id":"A1544","pred":"tao:has_database_id","subj":"1544","obj":"Gene:8673700"},{"id":"A1545","pred":"tao:has_database_id","subj":"1545","obj":"Gene:8673700"},{"id":"A1547","pred":"tao:has_database_id","subj":"1547","obj":"Tax:2697049"},{"subj":"1544","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1545","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1547","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T455","span":{"begin":0,"end":240},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T455","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-MONDO","color":"#da93ec","default":true},{"id":"LitCovid-PD-CLO","color":"#93ecc0"},{"id":"LitCovid-PD-CHEBI","color":"#eca693"},{"id":"LitCovid-PubTator","color":"#9399ec"},{"id":"LitCovid-sentences","color":"#b3ec93"}]}]}}