PMC:7461420 / 51206-51446
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T248 | 76-80 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T648 | 121-123 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T649 | 141-150 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
| T650 | 167-175 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T71965 | 61-75 | Chemical | denotes | peptidomimetic | http://purl.obolibrary.org/obo/CHEBI_63175 |
| T35724 | 87-102 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T19702 | 92-102 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1544 | 87-91 | Gene | denotes | Mpro | Gene:8673700 |
| 1545 | 188-192 | Gene | denotes | Mpro | Gene:8673700 |
| 1547 | 76-86 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T455 | 0-240 | Sentence | denotes | Very recently, Dai et al. designed and synthesized two novel peptidomimetic SARS‐CoV‐2 Mpro inhibitors 61 and 62 (Figure 18) which exhibited extremely high inhibitory activity on purified Mpro with IC50 values of 50 and 40 nM, respectively. |