PMC:7461420 / 44302-44749
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T213 | 141-149 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T214 | 206-214 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T215 | 430-438 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T544 | 34-35 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T545 | 62-63 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T456 | 12-22 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T457 | 44-52 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T458 | 53-58 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T459 | 141-157 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T460 | 141-149 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T461 | 206-222 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T462 | 206-214 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T463 | 273-281 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T464 | 282-287 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T465 | 412-421 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T466 | 430-446 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T467 | 430-438 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T57 | 375-384 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1343 | 141-149 | Chemical | denotes | cysteine | MESH:D003545 |
| 1344 | 206-214 | Chemical | denotes | cysteine | MESH:D003545 |
| 1345 | 324-335 | Chemical | denotes | α‐carbanion | |
| 1346 | 341-344 | Chemical | denotes | His | MESH:D006639 |
| 1347 | 430-438 | Chemical | denotes | cysteine | MESH:D003545 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T404 | 195-298 | Sentence | denotes | First, the cysteine residue undergoes 1,4‐addition at the inhibitor's Michael acceptor group (warhead). |
| T405 | 299-447 | Sentence | denotes | Rapid protonation of the α‐carbanion from His‐H+ leads to the covalent bond formation between the warhead of the inhibitor and the cysteine residue. |