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PMC:7456455 / 5075-7304 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T66 7-35 Body_part denotes mononuclear phagocyte system http://purl.org/sig/ont/fma/fma84189
T67 37-40 Body_part denotes MPS http://purl.org/sig/ont/fma/fma84189
T68 46-49 Body_part denotes MPS http://purl.org/sig/ont/fma/fma84189
T69 65-70 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T70 95-99 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T71 138-143 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T72 150-176 Body_part denotes Tissue resident macrophage http://purl.org/sig/ont/fma/fma84644
T73 150-156 Body_part denotes Tissue http://purl.org/sig/ont/fma/fma9637
T74 274-285 Body_part denotes bone marrow http://purl.org/sig/ont/fma/fma9608
T75 294-303 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T76 328-335 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T77 396-402 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T78 416-424 Body_part denotes Monocyte http://purl.org/sig/ont/fma/fma62864
T79 434-445 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T80 535-557 Body_part denotes mononuclear phagocytes http://purl.org/sig/ont/fma/fma273563
T81 588-603 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T82 678-683 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T83 772-781 Body_part denotes Monocytes http://purl.org/sig/ont/fma/fma62864
T84 786-797 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T85 984-989 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T86 1120-1126 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T87 1168-1174 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T88 1248-1253 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T89 1302-1311 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T90 1313-1323 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T91 1350-1356 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T92 1550-1561 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T93 1712-1725 Body_part denotes B lymphocytes http://purl.org/sig/ont/fma/fma62869
T94 1727-1749 Body_part denotes mononuclear phagocytes http://purl.org/sig/ont/fma/fma273563
T95 2071-2080 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T96 2096-2100 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T16 65-70 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T17 138-143 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T18 150-156 Body_part denotes Tissue http://purl.obolibrary.org/obo/UBERON_0000479
T19 274-285 Body_part denotes bone marrow http://purl.obolibrary.org/obo/UBERON_0002371
T20 396-402 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T21 1120-1126 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T22 1168-1174 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T30 37-40 Disease denotes MPS http://purl.obolibrary.org/obo/MONDO_0019249
T31 46-49 Disease denotes MPS http://purl.obolibrary.org/obo/MONDO_0019249
T32 382-391 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T33 473-485 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T34 489-497 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T35 1007-1019 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T36 1175-1181 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T37 1500-1512 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T95 7-28 http://purl.obolibrary.org/obo/CL_0000113 denotes mononuclear phagocyte
T96 53-54 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 65-70 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T98 138-143 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T99 150-176 http://purl.obolibrary.org/obo/CL_0000864 denotes Tissue resident macrophage
T100 274-278 http://purl.obolibrary.org/obo/UBERON_0002481 denotes bone
T101 294-303 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T102 416-424 http://purl.obolibrary.org/obo/CL_0000576 denotes Monocyte
T103 511-513 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T104 535-557 http://purl.obolibrary.org/obo/CL_0000113 denotes mononuclear phagocytes
T105 566-567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 588-594 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T107 595-603 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T108 661-670 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T109 661-670 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T110 678-683 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T111 730-739 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T112 755-765 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T113 772-781 http://purl.obolibrary.org/obo/CL_0000576 denotes Monocytes
T114 815-825 http://purl.obolibrary.org/obo/CL_0000234 denotes phagocytes
T115 837-839 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T116 950-956 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T117 984-989 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T118 1248-1253 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T119 1341-1349 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T120 1350-1356 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T121 1569-1579 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T122 1623-1625 http://purl.obolibrary.org/obo/CLO_0007448 denotes M1
T123 1623-1625 http://purl.obolibrary.org/obo/CLO_0050175 denotes M1
T124 1712-1713 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T125 1727-1749 http://purl.obolibrary.org/obo/CL_0000113 denotes mononuclear phagocytes
T126 1793-1794 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 1920-1930 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T128 1992-2002 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T129 2010-2011 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 2122-2124 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 1075-1088 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T16 1435-1441 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T17 1443-1451 Chemical denotes nitrogen http://purl.obolibrary.org/obo/CHEBI_25555
T18 1456-1468 Chemical denotes arachidonate http://purl.obolibrary.org/obo/CHEBI_32395
T19 1469-1480 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T20 1623-1625 Chemical denotes M1 http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826
T24 1654-1656 Chemical denotes M2 http://purl.obolibrary.org/obo/CHEBI_34827|http://purl.obolibrary.org/obo/CHEBI_51112
T26 1754-1761 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T27 2024-2032 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T28 2089-2091 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T30 2096-2098 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T32 2110-2120 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T33 2157-2161 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T34 2194-2209 Chemical denotes glucocorticoids http://purl.obolibrary.org/obo/CHEBI_24261
T35 2214-2228 Chemical denotes prostaglandins http://purl.obolibrary.org/obo/CHEBI_26333

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T20 473-485 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T21 730-739 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T22 1007-1019 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T23 1120-1138 http://purl.obolibrary.org/obo/GO_0001894 denotes tissue homeostasis
T24 1127-1138 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T25 1357-1368 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T26 1373-1392 http://purl.obolibrary.org/obo/GO_0006956 denotes complement cascades
T27 1500-1512 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T28 1550-1579 http://purl.obolibrary.org/obo/GO_0046649 denotes lymphocytes, their activation
T29 1813-1819 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T30 1874-1886 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T31 2143-2149 http://purl.obolibrary.org/obo/GO_0040007 denotes growth

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T33 0-41 Sentence denotes 2 The mononuclear phagocyte system (MPS)
T34 42-149 Sentence denotes The MPS is a dispersed organ, present throughout the body, with distinctive properties in every organ [21].
T35 150-415 Sentence denotes Tissue resident macrophage populations in the adult derive from embryonic progenitors and differ markedly in phenotype from bone marrow-derived monocytes, which are recruited to tissues in response to increased demand, for instance infection and tissue damage [19].
T36 416-528 Sentence denotes Monocyte- derived macrophages are the main generators of inflammation in COVID-19 [2,17,18,20,[22], [23], [24]].
T37 529-771 Sentence denotes These mononuclear phagocytes express a broad repertoire of plasma membrane and intracellular receptors, serving as sensors of micro-organisms, dying cells and soluble products, to mediate recognition, signaling, migration and activation [19].
T38 772-1103 Sentence denotes Monocytes and macrophages are professional phagocytes, utilizing Fc, complement, Toll-like and non-opsonic lectin-like and scavenger receptors for ingestion, but are also highly active biosynthetic and secretory cells, contributing to inflammation, innate and adaptive cellular and humoral immunity and antimicrobial defences [21].
T39 1104-1214 Sentence denotes While promoting tissue homeostasis and repair, they also induce tissue injury, the proverbial two-edged sword.
T40 1215-1533 Sentence denotes They interact readily with other cells through contact and soluble mediators including cytokines, chemokines and enzymes that activate plasma coagulation and complement cascades [24]; in addition, they generate reactive oxygen, nitrogen and arachidonate metabolites implicated in host inflammation and resolution [25].
T41 1534-1698 Sentence denotes By analogy with lymphocytes, their activation status is characterized for convenience as M1-type (pro-inflammatory) and M2-type (anti-inflammatory, reparative) [7].
T42 1699-1978 Sentence denotes Unlike T and B lymphocytes, mononuclear phagocytes are antigen non-specific, and only display a transient form of memory [26], primed to adapt to secondary challenges such as phagocytosis and microbial stimuli by further activation of potent secretory and cytotoxic pathways [7].
T43 1979-2229 Sentence denotes The level of activation covers a spectrum of effector mechanisms, constrained by inhibitory cytokines such as IL-10, IL-1 receptor antagonist [27] and transforming growth factor beta TGF-β, and by anti-inflammatory glucocorticoids and prostaglandins.

2_test

Id Subject Object Predicate Lexical cue
32861199-28662662-26409802 145-147 28662662 denotes 21
32861199-30332628-26409803 411-413 30332628 denotes 19
32861199-32610079-26409804 499-500 32610079 denotes 2
32861199-32534467-26409805 507-509 32534467 denotes 20
32861199-32278362-26409806 511-513 32278362 denotes 22
32861199-32377375-26409807 517-519 32377375 denotes 23
32861199-30332628-26409808 767-769 30332628 denotes 19
32861199-28662662-26409809 1099-1101 28662662 denotes 21
32861199-24669294-26409810 1695-1696 24669294 denotes 7
32861199-24669294-26409811 1975-1976 24669294 denotes 7

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T164 7-18 GO:0005634;CL:0000113 denotes mononuclear
T165 19-28 CL:0000113 denotes phagocyte
T166 65-70 UBERON:0000062 denotes organ
T167 138-143 UBERON:0000062 denotes organ
T168 150-156 UBERON:0000479 denotes Tissue
T169 166-176 CL:0000864 denotes macrophage
T170 196-201 UBERON:0007023 denotes adult
T171 214-223 UBERON:0000922 denotes embryonic
T172 274-285 UBERON:0002371 denotes bone marrow
T173 294-303 CL:0000576 denotes monocytes
T174 328-335 UBERON:0000479 denotes tissues
T175 396-402 UBERON:0000479 denotes tissue
T176 416-424 CL:0000576 denotes Monocyte
T177 434-445 CL:0000235 denotes macrophages
T178 489-497 SP_7 denotes COVID-19
T179 535-546 GO:0005634;CL:0000113 denotes mononuclear
T180 547-557 CL:0000113 denotes phagocytes
T181 558-565 GO:0010467 denotes express
T182 588-603 GO:0005886 denotes plasma membrane
T183 608-621 GO:0005622 denotes intracellular
T184 661-670 NCBITaxon:1 denotes organisms
T185 672-677 GO:0016265 denotes dying
T186 772-781 CL:0000576 denotes Monocytes
T187 786-797 CL:0000235 denotes macrophages
T188 815-825 CL:0000234 denotes phagocytes
T189 974-989 CL:0000151 denotes secretory cells
T190 1021-1027 GO:0045087 denotes innate
T191 1041-1049 GO:0006968 denotes cellular
T192 1075-1088 CHEBI:67079;CHEBI:67079 denotes antimicrobial
T193 1120-1126 UBERON:0000479;GO:0001894 denotes tissue
T194 1127-1138 GO:0001894 denotes homeostasis
T195 1168-1174 UBERON:0000479 denotes tissue
T196 1350-1356 UBERON:0001969 denotes plasma
T197 1357-1368 GO:0050817 denotes coagulation
T198 1373-1392 GO:0006956 denotes complement cascades
T199 1426-1434 CHEBI:26523;CHEBI:26523 denotes reactive
T200 1469-1480 CHEBI:25212;CHEBI:25212 denotes metabolites
T201 1550-1561 CL:0000542 denotes lymphocytes
T202 1706-1707 CL:0000084 denotes T
T203 1712-1725 CL:0000236 denotes B lymphocytes
T204 1727-1738 GO:0005634;CL:0000113 denotes mononuclear
T205 1739-1749 CL:0000113 denotes phagocytes
T206 1754-1761 CHEBI:59132;CHEBI:59132 denotes antigen
T207 1813-1819 GO:0007613 denotes memory
T208 1874-1886 GO:0006909 denotes phagocytosis
T209 2024-2032 CHEBI:35224;CHEBI:35224 denotes effector
T210 2089-2094 PR:000001471 denotes IL-10
T211 2101-2120 CHEBI:48561;CHEBI:48561 denotes receptor antagonist
T212 2130-2167 PR:000000046 denotes transforming growth factor beta TGF-β
T213 2176-2193 CHEBI:35472;CHEBI:35472 denotes anti-inflammatory
T214 2194-2209 CHEBI:24261;CHEBI:24261 denotes glucocorticoids
T215 2214-2228 CHEBI:26333;CHEBI:26333 denotes prostaglandins

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
103 37-40 Disease denotes MPS MESH:D009084
117 2089-2094 Gene denotes IL-10 Gene:3586
118 2096-2120 Gene denotes IL-1 receptor antagonist Gene:3557
119 2162-2167 Gene denotes TGF-β Gene:7039
120 1435-1441 Chemical denotes oxygen MESH:D010100
121 1443-1451 Chemical denotes nitrogen MESH:D009584
122 1456-1468 Chemical denotes arachidonate MESH:D016718
123 2214-2228 Chemical denotes prostaglandins MESH:D011453
124 46-49 Disease denotes MPS MESH:D009084
125 382-391 Disease denotes infection MESH:D007239
126 473-485 Disease denotes inflammation MESH:D007249
127 489-497 Disease denotes COVID-19 MESH:C000657245
128 1007-1019 Disease denotes inflammation MESH:D007249
129 1500-1512 Disease denotes inflammation MESH:D007249

MyTest

Id Subject Object Predicate Lexical cue
32861199-28662662-26409802 145-147 28662662 denotes 21
32861199-30332628-26409803 411-413 30332628 denotes 19
32861199-32610079-26409804 499-500 32610079 denotes 2
32861199-32534467-26409805 507-509 32534467 denotes 20
32861199-32278362-26409806 511-513 32278362 denotes 22
32861199-32377375-26409807 517-519 32377375 denotes 23
32861199-30332628-26409808 767-769 30332628 denotes 19
32861199-28662662-26409809 1099-1101 28662662 denotes 21
32861199-24669294-26409810 1695-1696 24669294 denotes 7
32861199-24669294-26409811 1975-1976 24669294 denotes 7