PMC:7456455 / 20564-21765
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T264 | 75-85 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
| T265 | 114-119 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T266 | 124-130 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T267 | 185-193 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
| T268 | 218-228 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
| T269 | 290-294 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T270 | 295-298 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T271 | 311-320 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T272 | 333-353 | Body_part | denotes | alveolar macrophages | http://purl.org/sig/ont/fma/fma83023 |
| T273 | 462-473 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T274 | 494-498 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T275 | 499-511 | Body_part | denotes | interstitium | http://purl.org/sig/ont/fma/fma86301 |
| T276 | 513-528 | Body_part | denotes | Plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
| T277 | 513-519 | Body_part | denotes | Plasma | http://purl.org/sig/ont/fma/fma62970 |
| T278 | 598-607 | Body_part | denotes | monocytic | http://purl.org/sig/ont/fma/fma62864 |
| T279 | 684-689 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T280 | 723-726 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T281 | 728-731 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T282 | 961-965 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T283 | 1016-1038 | Body_part | denotes | mononuclear phagocytes | http://purl.org/sig/ont/fma/fma273563 |
| T284 | 1053-1059 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T285 | 1146-1151 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T286 | 1153-1162 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
| T287 | 1191-1200 | Body_part | denotes | epithelia | http://purl.org/sig/ont/fma/fma9639 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T71 | 114-119 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T72 | 124-130 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T73 | 261-267 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
| T74 | 494-498 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T75 | 1191-1200 | Body_part | denotes | epithelia | http://purl.obolibrary.org/obo/UBERON_0000483 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T145 | 63-67 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T146 | 143-151 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T147 | 274-278 | Disease | denotes | FACS | http://purl.obolibrary.org/obo/MONDO_0018262 |
| T148 | 584-596 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T297 | 114-119 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T298 | 114-119 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T299 | 185-193 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
| T300 | 229-239 | http://purl.obolibrary.org/obo/CL_0000234 | denotes | phagocytic |
| T301 | 240-248 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T302 | 261-267 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs |
| T303 | 290-294 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T304 | 311-320 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T305 | 355-357 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T306 | 452-461 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
| T307 | 494-498 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T308 | 494-498 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T309 | 499-511 | http://purl.obolibrary.org/obo/UBERON_0005169 | denotes | interstitium |
| T310 | 513-519 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | Plasma |
| T311 | 520-528 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T312 | 598-607 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytic |
| T313 | 637-647 | http://purl.obolibrary.org/obo/CL_0000234 | denotes | phagocytic |
| T314 | 684-689 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T315 | 754-763 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T316 | 974-976 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T317 | 985-987 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T318 | 998-1000 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T319 | 1016-1038 | http://purl.obolibrary.org/obo/CL_0000113 | denotes | mononuclear phagocytes |
| T320 | 1053-1059 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T321 | 1146-1151 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T85 | 728-731 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T86 | 842-851 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T87 | 961-963 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T89 | 979-981 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T91 | 1103-1112 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T84 | 584-596 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T85 | 754-772 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T86 | 754-763 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T122 | 0-105 | Sentence | denotes | Earlier studies on SARS1/MERS revealed many of the features of ARDS and of macrophage involvement [6,51]. |
| T123 | 106-273 | Sentence | denotes | Initial blood and tissue analysis of COVID-19 provided morphologic evidence of monocyte abnormality and intense macrophage phagocytic activity in infected organs [65]. |
| T124 | 274-512 | Sentence | denotes | FACS and single cell RNA analysis of monocytes and broncho-alveolar macrophages [18] provided evidence of emergency myelopoiesis [64] and confirmed the presence of recruited and activated macrophages in alveoli [17] and lung interstitium. |
| T125 | 513-701 | Sentence | denotes | Plasma membrane opsonic and other receptors contribute to dysregulated inflammation, monocytic hyperactivation and impaired phagocytic clearance of apoptotic and necrotic cells and debris. |
| T126 | 702-830 | Sentence | denotes | Acting through NFkB, RNA, DNA and other sensing and signaling pathways, they initiate production of numerous secretory products. |
| T127 | 831-1002 | Sentence | denotes | Particular antiviral and proinflammatory products have been targeted for anti-inflammatory treatment, including the IFNs [55,56], IL-1 family [52], IL-6 [27] and TNF [22]. |
| T128 | 1003-1201 | Sentence | denotes | In addition, mononuclear phagocytes interact with plasma cascades, and through upregulated adhesion molecules, with other myeloid and lymphoid cells, platelets, system-wide endothelia and epithelia. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-32145185-26409847 | 99-100 | 32145185 | denotes | 6 |
| 32861199-31883097-26409848 | 101-103 | 31883097 | denotes | 51 |
| 32861199-32651212-26409849 | 953-955 | 32651212 | denotes | 55 |
| 32861199-32278362-26409850 | 998-1000 | 32278362 | denotes | 22 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T545 | 19-24 | SP_10;PR:000014459 | denotes | SARS1 |
| T546 | 25-29 | SP_9 | denotes | MERS |
| T547 | 75-85 | CL:0000235 | denotes | macrophage |
| T548 | 114-119 | UBERON:0000178 | denotes | blood |
| T549 | 124-130 | UBERON:0000479 | denotes | tissue |
| T550 | 143-151 | SP_7 | denotes | COVID-19 |
| T551 | 185-193 | CL:0000576 | denotes | monocyte |
| T552 | 218-228 | CL:0000235 | denotes | macrophage |
| T553 | 229-239 | GO:0006909 | denotes | phagocytic |
| T554 | 261-267 | UBERON:0000062 | denotes | organs |
| T555 | 295-307 | BV_21 | denotes | RNA analysis |
| T556 | 311-320 | CL:0000576 | denotes | monocytes |
| T557 | 333-341 | UBERON:0003215;CL:0000583 | denotes | alveolar |
| T558 | 342-353 | CL:0000583 | denotes | macrophages |
| T559 | 452-461 | CL:0002627 | denotes | activated |
| T560 | 462-473 | CL:0000235 | denotes | macrophages |
| T561 | 477-484 | UBERON:0003215 | denotes | alveoli |
| T562 | 494-498 | UBERON:0002048 | denotes | lung |
| T563 | 499-511 | UBERON:0005169 | denotes | interstitium |
| T564 | 513-519 | UBERON:0001969;GO:0005886 | denotes | Plasma |
| T565 | 520-528 | GO:0005886 | denotes | membrane |
| T566 | 571-583 | GO:0065007 | denotes | dysregulated |
| T567 | 598-607 | CL:0000576 | denotes | monocytic |
| T568 | 637-647 | CL:0000234;GO:0043277 | denotes | phagocytic |
| T569 | 648-660 | GO:0043277 | denotes | clearance of |
| T570 | 661-670 | GO:0043277;CL:0000445 | denotes | apoptotic |
| T571 | 979-983 | PR:000001393 | denotes | IL-6 |
| T572 | 993-996 | PR:000000134 | denotes | TNF |
| T573 | 1016-1027 | GO:0005634;CL:0000113 | denotes | mononuclear |
| T574 | 1028-1038 | CL:0000113 | denotes | phagocytes |
| T575 | 1053-1059 | UBERON:0001969 | denotes | plasma |
| T576 | 1103-1112 | CHEBI:36357;CHEBI:36357 | denotes | molecules |
| T577 | 1125-1132 | CL:0000763 | denotes | myeloid |
| T578 | 1153-1162 | CL:0000233 | denotes | platelets |
| T579 | 1176-1186 | UBERON:0001986 | denotes | endothelia |
| T580 | 1191-1200 | UBERON:0000483 | denotes | epithelia |
| T32420 | 78-87 | CL:0002627 | denotes | rophage i |
| T65243 | 88-99 | CL:0000235 | denotes | volvement [ |
| T87236 | 103-110 | UBERON:0003215 | denotes | ]. Init |
| T25758 | 120-124 | UBERON:0002048 | denotes | and |
| T97343 | 125-137 | UBERON:0005169 | denotes | issue analys |
| T14499 | 139-145 | UBERON:0001969;GO:0005886 | denotes | of CO |
| T62772 | 146-154 | GO:0005886 | denotes | ID-19 pr |
| T54415 | 197-209 | GO:0065007 | denotes | ormality and |
| T92032 | 224-233 | CL:0000576 | denotes | hage phag |
| T4527 | 263-273 | CL:0000234;GO:0043277 | denotes | gans [65]. |
| T90878 | 274-286 | GO:0043277 | denotes | FACS and sin |
| T44930 | 287-296 | GO:0043277;CL:0000445 | denotes | le cell R |
| T22018 | 604-608 | PR:000001393 | denotes | tic |
| T14979 | 618-621 | PR:000000134 | denotes | ati |
| T94886 | 641-651 | GO:0005634;CL:0000113 | denotes | ocytic cle |
| T71746 | 652-662 | CL:0000113 | denotes | rance of a |
| T29095 | 677-683 | UBERON:0001969 | denotes | crotic |
| T94038 | 727-736 | CHEBI:36357;CHEBI:36357 | denotes | DNA and |
| T61651 | 749-756 | CL:0000763 | denotes | and si |
| T78507 | 777-786 | CL:0000233 | denotes | y initiat |
| T40475 | 800-811 | UBERON:0001986 | denotes | f numerous |
| T50898 | 816-824 | UBERON:0000483 | denotes | tory pro |
| T7591 | 826-838 | GO:0065007 | denotes | cts. Particu |
| T83118 | 839-852 | GO:0042116 | denotes | ar antiviral |
| T7851 | 853-864 | CL:0000235 | denotes | nd proinfla |
| T76040 | 906-916 | GO:0007596 | denotes | ti-inflamm |
| T84571 | 936-944 | SP_7 | denotes | luding t |
| T61834 | 982-991 | GO:0006915 | denotes | 6 [27] an |
| T14017 | 1052-1062 | CL:0000235 | denotes | plasma ca |
| T19719 | 1082-1090 | CHEBI:35224;CHEBI:35224 | denotes | upregula |
| T17572 | 1154-1169 | GO:0032612 | denotes | latelets, syste |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 501 | 25-29 | Disease | denotes | MERS | MESH:D018352 |
| 502 | 63-67 | Disease | denotes | ARDS | MESH:D012128 |
| 503 | 143-151 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 504 | 252-260 | Disease | denotes | infected | MESH:D007239 |
| 505 | 390-402 | Disease | denotes | myelopoiesis | MESH:C563551 |
| 506 | 584-596 | Disease | denotes | inflammation | MESH:D007249 |
| 507 | 675-683 | Disease | denotes | necrotic | MESH:D009336 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-32145185-26409847 | 99-100 | 32145185 | denotes | 6 |
| 32861199-31883097-26409848 | 101-103 | 31883097 | denotes | 51 |
| 32861199-32651212-26409849 | 953-955 | 32651212 | denotes | 55 |
| 32861199-32278362-26409850 | 998-1000 | 32278362 | denotes | 22 |