PMC:7455777 / 714-1215 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":44,"end":56},"obj":"Body_part"},{"id":"T2","span":{"begin":90,"end":103},"obj":"Body_part"},{"id":"T3","span":{"begin":90,"end":94},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T8","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"T9","span":{"begin":60,"end":68},"obj":"Disease"},{"id":"T10","span":{"begin":373,"end":381},"obj":"Disease"},{"id":"T11","span":{"begin":426,"end":434},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T11","span":{"begin":14,"end":15},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":90,"end":94},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T13","span":{"begin":95,"end":103},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T14","span":{"begin":242,"end":243},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":16,"end":20},"obj":"Chemical"},{"id":"T5","span":{"begin":44,"end":56},"obj":"Chemical"},{"id":"T6","span":{"begin":138,"end":149},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":0,"end":33},"obj":"Sentence"},{"id":"T8","span":{"begin":34,"end":284},"obj":"Sentence"},{"id":"T9","span":{"begin":285,"end":501},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T14","span":{"begin":0,"end":10},"obj":"SP_7"},{"id":"T15","span":{"begin":21,"end":32},"obj":"NCBITaxon:11118"},{"id":"T16","span":{"begin":38,"end":43},"obj":"PG_18;PG_1"},{"id":"T17","span":{"begin":44,"end":56},"obj":"PG_18;PG_1;CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T18","span":{"begin":60,"end":70},"obj":"SP_7"},{"id":"T19","span":{"begin":90,"end":103},"obj":"GO:0033644"},{"id":"T20","span":{"begin":138,"end":169},"obj":"PG_10;PR:000003622"},{"id":"T21","span":{"begin":171,"end":175},"obj":"G_3;PG_10;PR:000003622"},{"id":"T22","span":{"begin":191,"end":204},"obj":"GO:0016020"},{"id":"T23","span":{"begin":222,"end":229},"obj":"G_2;PR:000016456"},{"id":"T24","span":{"begin":265,"end":270},"obj":"NCBITaxon:10239;GO:0042148"},{"id":"T25","span":{"begin":271,"end":279},"obj":"GO:0042148"},{"id":"T26","span":{"begin":298,"end":306},"obj":"SO:0000853"},{"id":"T27","span":{"begin":336,"end":342},"obj":"SO:0000417"},{"id":"T28","span":{"begin":373,"end":383},"obj":"SP_7"},{"id":"T29","span":{"begin":426,"end":434},"obj":"SP_10"},{"id":"T91766","span":{"begin":0,"end":10},"obj":"SP_7"},{"id":"T98252","span":{"begin":21,"end":32},"obj":"NCBITaxon:11118"},{"id":"T85594","span":{"begin":38,"end":43},"obj":"PG_18;PG_1"},{"id":"T45057","span":{"begin":44,"end":56},"obj":"PG_18;PG_1;CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T13328","span":{"begin":60,"end":70},"obj":"SP_7"},{"id":"T96603","span":{"begin":90,"end":103},"obj":"GO:0033644"},{"id":"T13578","span":{"begin":138,"end":169},"obj":"PG_10;PR:000003622"},{"id":"T34881","span":{"begin":171,"end":175},"obj":"G_3;PG_10;PR:000003622"},{"id":"T72872","span":{"begin":191,"end":204},"obj":"GO:0016020"},{"id":"T81428","span":{"begin":222,"end":229},"obj":"G_2;PR:000016456"},{"id":"T44662","span":{"begin":265,"end":270},"obj":"NCBITaxon:10239;GO:0042148"},{"id":"T81441","span":{"begin":271,"end":279},"obj":"GO:0042148"},{"id":"T91664","span":{"begin":298,"end":306},"obj":"SO:0000853"},{"id":"T5861","span":{"begin":336,"end":342},"obj":"SO:0000417"},{"id":"T95071","span":{"begin":373,"end":383},"obj":"SP_7"},{"id":"T22728","span":{"begin":426,"end":434},"obj":"SP_10"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"28","span":{"begin":138,"end":169},"obj":"Gene"},{"id":"29","span":{"begin":171,"end":175},"obj":"Gene"},{"id":"30","span":{"begin":222,"end":229},"obj":"Gene"},{"id":"31","span":{"begin":0,"end":10},"obj":"Species"},{"id":"32","span":{"begin":16,"end":32},"obj":"Species"},{"id":"33","span":{"begin":60,"end":70},"obj":"Species"},{"id":"34","span":{"begin":373,"end":383},"obj":"Species"},{"id":"35","span":{"begin":426,"end":434},"obj":"Species"}],"attributes":[{"id":"A28","pred":"tao:has_database_id","subj":"28","obj":"Gene:59272"},{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"Gene:59272"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Gene:7113"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"Tax:2697049"},{"id":"A32","pred":"tao:has_database_id","subj":"32","obj":"Tax:694002"},{"id":"A33","pred":"tao:has_database_id","subj":"33","obj":"Tax:2697049"},{"id":"A34","pred":"tao:has_database_id","subj":"34","obj":"Tax:2697049"},{"id":"A35","pred":"tao:has_database_id","subj":"35","obj":"Tax:694009"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV-2 is a beta-coronavirus. The spike glycoprotein of SARS-CoV-2 can attach to host cell membrane by recognizing and binding to the angiotensin-converting enzyme 2 (ACE2) receptor, and transmembrane protease type 2 (TMPRSS2) also plays a critical role in the viral invasion [1]. Based on the homology modeling of receptor binding domain subdomain-1, the structure of SARS-CoV-2 shows about 73.96% sequence identity with SARS-CoV, which might explain the resemblance in biochemical mechanism [2]."}