PMC:7455777 / 5088-6087
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T37 | 63-66 | Body_part | denotes | CNS | http://purl.org/sig/ont/fma/fma55675 |
T38 | 217-237 | Body_part | denotes | olfactory epithelium | http://purl.org/sig/ont/fma/fma64803 |
T39 | 227-237 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
T40 | 266-273 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T41 | 302-320 | Body_part | denotes | non-neuronal cells | http://purl.org/sig/ont/fma/fma54536 |
T42 | 315-320 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T43 | 364-369 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T44 | 371-381 | Body_part | denotes | stem cells | http://purl.org/sig/ont/fma/fma63368 |
T45 | 376-381 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T46 | 396-405 | Body_part | denotes | pericytes | http://purl.org/sig/ont/fma/fma63174 |
T47 | 502-506 | Body_part | denotes | bulb | http://purl.org/sig/ont/fma/fma62004 |
T48 | 507-514 | Body_part | denotes | neurons | http://purl.org/sig/ont/fma/fma54527 |
T49 | 542-560 | Body_part | denotes | non-neuronal cells | http://purl.org/sig/ont/fma/fma54536 |
T50 | 555-560 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T51 | 684-691 | Body_part | denotes | neurons | http://purl.org/sig/ont/fma/fma54527 |
T52 | 810-825 | Body_part | denotes | olfactory bulbs | http://purl.org/sig/ont/fma/fma77624 |
T53 | 968-972 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T54 | 976-998 | Body_part | denotes | gastrointestinal tract | http://purl.org/sig/ont/fma/fma71132 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T26 | 63-66 | Body_part | denotes | CNS | http://purl.obolibrary.org/obo/UBERON_0001017 |
T27 | 217-237 | Body_part | denotes | olfactory epithelium | http://purl.obolibrary.org/obo/UBERON_0001997 |
T28 | 227-237 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
T29 | 810-825 | Body_part | denotes | olfactory bulbs | http://purl.obolibrary.org/obo/UBERON_0002264 |
T30 | 968-972 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T49 | 27-35 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T50 | 158-166 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T51 | 194-209 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
T52 | 200-209 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T53 | 447-455 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T54 | 458-467 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T55 | 529-538 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T77 | 63-66 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | CNS |
T78 | 63-66 | http://www.ebi.ac.uk/efo/EFO_0000908 | denotes | CNS |
T79 | 63-66 | http://purl.obolibrary.org/obo/UBERON_0001017 | denotes | CNS |
T80 | 227-237 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
T81 | 260-273 | http://purl.obolibrary.org/obo/PR_000029067 | denotes | Human Protein |
T82 | 315-320 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T83 | 345-355 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T84 | 356-369 | http://purl.obolibrary.org/obo/CL_0000630 | denotes | support cells |
T85 | 371-381 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
T86 | 555-560 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T87 | 723-730 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signals |
T88 | 778-783 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T89 | 952-958 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
T90 | 968-972 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T91 | 968-972 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T92 | 976-998 | http://purl.obolibrary.org/obo/UBERON_0005409 | denotes | gastrointestinal tract |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T7 | 266-273 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T8 | 281-284 | Chemical | denotes | HPA | http://purl.obolibrary.org/obo/CHEBI_29031|http://purl.obolibrary.org/obo/CHEBI_53393|http://purl.obolibrary.org/obo/CHEBI_61431|http://purl.obolibrary.org/obo/CHEBI_64342 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 194-209 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
T4 | 625-647 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory responses |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T31 | 0-97 | Sentence | denotes | It remains unclear whether SARS-CoV-2 is able to penetrate the CNS via neuronal retrograde route. |
T32 | 98-238 | Sentence | denotes | Olfactory dysfunction is one of the most common symptoms in COVID-19, which is often related to viral infection of the olfactory epithelium. |
T33 | 239-520 | Sentence | denotes | But according to the Human Protein Atlas (HPA) database, it is non-neuronal cells (for example, olfactory epithelial support cells, stem cells, and vascular pericytes) that express ACE2 and are vulnerable to SARS-CoV-2 infection, rather than olfactory sensory or bulb neurons [12]. |
T34 | 521-731 | Sentence | denotes | Primary infection of non-neuronal cells possibly causes olfactory dysfunction by leading to significant inflammatory responses, altering the function of olfactory neurons, and influencing the olfactory signals. |
T35 | 732-851 | Sentence | denotes | Besides, no specific changes referable to the virus have been observed in the olfactory bulbs or tracts at autopsy [6]. |
T36 | 852-999 | Sentence | denotes | Thus, further studies may be needed to determine whether there are other neuronal pathways, such as nerves from the lung or gastrointestinal tract. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T105 | 27-37 | SP_7 | denotes | SARS-CoV-2 |
T106 | 63-66 | UBERON:0001017 | denotes | CNS |
T107 | 71-79 | CL:0000540 | denotes | neuronal |
T108 | 98-107 | GO:0007608 | denotes | Olfactory |
T109 | 158-166 | SP_7 | denotes | COVID-19 |
T110 | 194-199 | NCBITaxon:10239 | denotes | viral |
T111 | 217-226 | GO:0007608;UBERON:0001997 | denotes | olfactory |
T112 | 227-237 | UBERON:0001997 | denotes | epithelium |
T113 | 260-265 | SP_6;NCBITaxon:9606 | denotes | Human |
T114 | 306-314 | CL:0000540 | denotes | neuronal |
T115 | 335-344 | GO:0007608;UBERON:0001997;CL:0000853 | denotes | olfactory |
T116 | 345-355 | UBERON:0001997;CL:0000853 | denotes | epithelial |
T117 | 356-369 | CL:0000853 | denotes | support cells |
T118 | 371-381 | CL:0000034 | denotes | stem cells |
T119 | 396-405 | CL:0000669 | denotes | pericytes |
T120 | 412-419 | GO:0010467 | denotes | express |
T121 | 420-424 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T122 | 447-451 | PR:000014459;SP_7 | denotes | SARS |
T123 | 451-457 | SP_7 | denotes | -CoV-2 |
T124 | 481-490 | GO:0007608;CL:0000207 | denotes | olfactory |
T125 | 491-498 | CL:0000207 | denotes | sensory |
T126 | 507-514 | CL:0000540 | denotes | neurons |
T127 | 546-554 | CL:0000540 | denotes | neuronal |
T128 | 577-586 | GO:0007608 | denotes | olfactory |
T129 | 674-683 | CL:0000207;GO:0007608 | denotes | olfactory |
T130 | 684-691 | CL:0000540 | denotes | neurons |
T131 | 713-722 | GO:0007608 | denotes | olfactory |
T132 | 778-783 | NCBITaxon:10239 | denotes | virus |
T133 | 810-819 | GO:0007608;UBERON:0002264 | denotes | olfactory |
T134 | 820-825 | UBERON:0002264 | denotes | bulbs |
T135 | 925-933 | CL:0000540 | denotes | neuronal |
T136 | 952-958 | UBERON:0001021 | denotes | nerves |
T137 | 968-972 | UBERON:0002048 | denotes | lung |
T138 | 976-998 | UBERON:0001555 | denotes | gastrointestinal tract |
T3336 | 9-14 | UBERON:0002264 | denotes | s unc |
T73156 | 114-122 | CL:0000540 | denotes | ction is |
T3243 | 141-147 | UBERON:0001021 | denotes | mmon s |
T75854 | 157-161 | UBERON:0002048 | denotes | COV |
T6635 | 165-187 | UBERON:0001555 | denotes | 9, which is often rela |
T14312 | 295-305 | SP_7 | denotes | it is non |
T99229 | 309-327 | UBERON:0001359 | denotes | ronal cells (for e |
T42859 | 329-332 | UBERON:0001359 | denotes | mpl |
T13748 | 392-402 | SP_7 | denotes | lar pericy |
T39664 | 448-453 | NCBITaxon:10239 | denotes | ARS-C |
T42828 | 463-471 | UBERON:0010743 | denotes | tion, ra |
T68773 | 476-484 | UBERON:0001893 | denotes | than olf |
T45301 | 485-502 | UBERON:0002049 | denotes | ctory sensory or |
T83636 | 543-549 | UBERON:0000479 | denotes | on-neu |
T99415 | 550-560 | GO:0010467 | denotes | onal cells |
T23142 | 583-586 | UBERON:0001017;CL:0000117 | denotes | ory |
T30604 | 587-592 | CL:0000117 | denotes | dysfu |
T33002 | 593-600 | GO:0010467 | denotes | ction b |
T71452 | 622-629 | G_2;PR:000016456 | denotes | nt infl |
T72350 | 653-663 | SP_7 | denotes | ring the f |
T58064 | 673-683 | GO:0035376 | denotes | olfactory |
T59513 | 750-760 | SP_7 | denotes | ic changes |
T24395 | 776-781 | SP_6;NCBITaxon:9606 | denotes | e vir |
T42636 | 790-811 | CL:0002248 | denotes | een observed in the o |
T43328 | 870-881 | GO:0006260 | denotes | ies may be |
T26162 | 901-912 | UBERON:0000955 | denotes | whether the |
T14083 | 924-931 | G_2;PR:000016456 | denotes | neuron |
T31777 | 932-936 | SO:0000704;GO:0010467 | denotes | l pa |
T53408 | 937-947 | GO:0010467 | denotes | hways, suc |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
146 | 420-424 | Gene | denotes | ACE2 | Gene:59272 |
147 | 27-37 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
148 | 260-265 | Species | denotes | Human | Tax:9606 |
149 | 98-119 | Disease | denotes | Olfactory dysfunction | MESH:D000857 |
150 | 158-166 | Disease | denotes | COVID-19 | MESH:C000657245 |
151 | 194-209 | Disease | denotes | viral infection | MESH:D001102 |
152 | 281-284 | Disease | denotes | HPA | MESH:D010661 |
153 | 447-467 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
154 | 521-538 | Disease | denotes | Primary infection | MESH:D007239 |
155 | 577-598 | Disease | denotes | olfactory dysfunction | MESH:D000857 |