PMC:7449695 / 26969-27876 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T87","span":{"begin":149,"end":150},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The delay from symptom onset to reporting is likely to decrease over the course of the epidemic, due to improved surveillance and reporting. We used a delay distribution estimated from observed reporting delays from the analysis period, which is therefore likely to underestimate reporting delays early in the epidemic, and overestimate them as the epidemic progressed. Underestimating the delay would result in an overestimate of R𝑒𝑓𝑓, as the inferred onset dates (for those that were unknown) and adjustment for right-truncation, would result in more concentrated inferred daily cases (i.e., the inferred cases would be more clustered in time than in reality). The converse would be true when overestimating the delay. The impact of this misspecified distribution will be greatest on the most recent estimates of R𝑒𝑓𝑓, where inference for both right-truncation and missing symptom onset dates is required."}

{"project":"LitCovid-sentences","denotations":[{"id":"T188","span":{"begin":0,"end":140},"obj":"Sentence"},{"id":"T189","span":{"begin":141,"end":369},"obj":"Sentence"},{"id":"T190","span":{"begin":370,"end":662},"obj":"Sentence"},{"id":"T191","span":{"begin":663,"end":720},"obj":"Sentence"},{"id":"T192","span":{"begin":721,"end":907},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The delay from symptom onset to reporting is likely to decrease over the course of the epidemic, due to improved surveillance and reporting. We used a delay distribution estimated from observed reporting delays from the analysis period, which is therefore likely to underestimate reporting delays early in the epidemic, and overestimate them as the epidemic progressed. Underestimating the delay would result in an overestimate of R𝑒𝑓𝑓, as the inferred onset dates (for those that were unknown) and adjustment for right-truncation, would result in more concentrated inferred daily cases (i.e., the inferred cases would be more clustered in time than in reality). The converse would be true when overestimating the delay. The impact of this misspecified distribution will be greatest on the most recent estimates of R𝑒𝑓𝑓, where inference for both right-truncation and missing symptom onset dates is required."}