PMC:7441788 / 5260-5969
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T15 | 100-104 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T16 | 416-420 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T17 | 533-538 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T18 | 589-600 | Body_part | denotes | spinal cord | http://purl.org/sig/ont/fma/fma7647 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 100-104 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T2 | 416-420 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T3 | 533-538 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T4 | 589-600 | Body_part | denotes | spinal cord | http://purl.obolibrary.org/obo/UBERON_0002240 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T50 | 557-566 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T50 | 58-66 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T51 | 120-125 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T52 | 257-258 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T53 | 468-473 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T54 | 533-538 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
| T55 | 533-538 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
| T56 | 589-600 | http://purl.obolibrary.org/obo/UBERON_0002240 | denotes | spinal cord |
| T57 | 652-653 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T58 | 679-687 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T65 | 28-30 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T66 | 221-223 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T67 | 346-348 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T68 | 448-450 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T69 | 481-483 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T70 | 640-642 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T42 | 28-30 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T43 | 221-223 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T44 | 346-348 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T45 | 448-450 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T46 | 481-483 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T47 | 640-642 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T48 | 48-57 | Species | denotes | HCoV-OC43 | NCBItxid:31631 |
| T49 | 120-125 | Species | denotes | mouse | NCBItxid:10090|NCBItxid:10088 |
| T51 | 186-190 | Species | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T53 | 398-402 | Species | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T55 | 468-473 | Species | denotes | mouse | NCBItxid:10090|NCBItxid:10088 |
| T57 | 504-513 | Species | denotes | HCoV-OC43 | NCBItxid:31631 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T42 | 0-105 | Sentence | denotes | An in vivo study found that CQ could exert anti-HCoV-OC43 activity transplacentally or via maternal milk. |
| T43 | 106-368 | Sentence | denotes | The data from mouse models showed that 98.6% of the pups survived when pregnant mice were treated with 15 mg/kg of CQ, and survival rates decreased in a dose-dependent manner, with 88% and 13% survival when treated with 5 mg/kg and 1 mg/kg CQ, respectively [14]. |
| T44 | 369-456 | Sentence | denotes | The survival rate of newborn mice via maternal milk was 69.0% with 15 mg/kg of CQ [14]. |
| T45 | 457-606 | Sentence | denotes | In another mouse study, CQ strongly attenuated HCoV-OC43 replication in the brain and prevented the infection from spreading to the spinal cord [15]. |
| T46 | 607-709 | Sentence | denotes | The above studies confirmed that CQ/HCQ have a broad-spectrum anti-HCoV activity in vitro and in vivo. |
LitCovid-sample-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 100-104 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T2 | 416-420 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T3 | 533-538 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T4 | 589-600 | Body_part | denotes | spinal cord | http://purl.obolibrary.org/obo/UBERON_0002240 |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 228 | 120-125 | Species | denotes | mouse | Tax:10090 |
| 229 | 186-190 | Species | denotes | mice | Tax:10090 |
| 230 | 398-402 | Species | denotes | mice | Tax:10090 |
| 231 | 468-473 | Species | denotes | mouse | Tax:10090 |
| 232 | 504-513 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 233 | 48-57 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 234 | 28-30 | Chemical | denotes | CQ | MESH:D002738 |
| 235 | 221-223 | Chemical | denotes | CQ | MESH:D002738 |
| 236 | 346-348 | Chemical | denotes | CQ | MESH:D002738 |
| 237 | 448-450 | Chemical | denotes | CQ | MESH:D002738 |
| 238 | 481-483 | Chemical | denotes | CQ | MESH:D002738 |
| 239 | 557-566 | Disease | denotes | infection | MESH:D007239 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T42 | 514-525 | http://purl.obolibrary.org/obo/IDO_0000608 | denotes | replication |
| T43 | 557-566 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infection |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T15 | 100-104 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T16 | 416-420 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T17 | 533-538 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T18 | 589-600 | Body_part | denotes | spinal cord | http://purl.org/sig/ont/fma/fma7647 |
LitCovid-sample-PD-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 533-538 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
| T2 | 589-600 | http://purl.obolibrary.org/obo/MAT_0000183 | denotes | spinal cord |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T43 | 557-566 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 228 | 120-125 | Species | denotes | mouse | Tax:10090 |
| 229 | 186-190 | Species | denotes | mice | Tax:10090 |
| 230 | 398-402 | Species | denotes | mice | Tax:10090 |
| 231 | 468-473 | Species | denotes | mouse | Tax:10090 |
| 232 | 504-513 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 233 | 48-57 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 234 | 28-30 | Chemical | denotes | CQ | MESH:D002738 |
| 235 | 221-223 | Chemical | denotes | CQ | MESH:D002738 |
| 236 | 346-348 | Chemical | denotes | CQ | MESH:D002738 |
| 237 | 448-450 | Chemical | denotes | CQ | MESH:D002738 |
| 238 | 481-483 | Chemical | denotes | CQ | MESH:D002738 |
| 239 | 557-566 | Disease | denotes | infection | MESH:D007239 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T42 | 0-105 | Sentence | denotes | An in vivo study found that CQ could exert anti-HCoV-OC43 activity transplacentally or via maternal milk. |
| T43 | 106-368 | Sentence | denotes | The data from mouse models showed that 98.6% of the pups survived when pregnant mice were treated with 15 mg/kg of CQ, and survival rates decreased in a dose-dependent manner, with 88% and 13% survival when treated with 5 mg/kg and 1 mg/kg CQ, respectively [14]. |
| T44 | 369-456 | Sentence | denotes | The survival rate of newborn mice via maternal milk was 69.0% with 15 mg/kg of CQ [14]. |
| T45 | 457-606 | Sentence | denotes | In another mouse study, CQ strongly attenuated HCoV-OC43 replication in the brain and prevented the infection from spreading to the spinal cord [15]. |
| T46 | 607-709 | Sentence | denotes | The above studies confirmed that CQ/HCQ have a broad-spectrum anti-HCoV activity in vitro and in vivo. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32496926-19506054-132195662 | 364-366 | 19506054 | denotes | 14 |
| 32496926-19506054-132195663 | 452-454 | 19506054 | denotes | 14 |