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PMC:7441788 / 3515-4209 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T11 95-99 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 459-464 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T40 86-94 Disease denotes hepatoma http://purl.obolibrary.org/obo/MONDO_0007256
T41 484-493 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T42 574-583 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T25 14-22 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T26 80-85 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T27 95-104 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T28 106-111 http://purl.obolibrary.org/obo/CLO_0051864 denotes Huh-7
T29 452-464 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T30 509-514 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T31 639-644 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T42 4-13 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T43 26-28 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T44 301-303 Chemical denotes SI http://purl.obolibrary.org/obo/CHEBI_90326
T45 368-370 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T46 446-448 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T47 541-543 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T48 619-621 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T27 26-28 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T28 368-370 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T29 446-448 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T30 541-543 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T31 619-621 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T37 37-45 Species denotes MERS-CoV NCBItxid:1335626
T38 50-59 Species denotes HCoV-229E NCBItxid:11137
T39 80-85 Species denotes human NCBItxid:9606
T40 406-414 Species denotes MERS-CoV NCBItxid:1335626
T41 475-483 Species denotes MERS-CoV NCBItxid:1335626
T42 565-573 Species denotes MERS-CoV NCBItxid:1335626

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T32 0-367 Sentence denotes The antiviral activity of CQ against MERS-CoV and HCoV-229E was assessed in the human hepatoma cell line (Huh-7) and found that the 50% effective concentrations (EC50) were 3.0(±1.1) μM and 3.3(±1.2) μM, the 50% cytotoxic concentrations (CC50) were 58.1(±1.1) μM and >50, and the selectivity indexes (SI; calculated as CC50/EC50) were 19.4 and >15, respectively [10].
T33 368-433 Sentence denotes CQ could inhibit an early step in the MERS-CoV replication cycle.
T34 434-526 Sentence denotes Addition of CQ to VeroE6 cells 1 h after MERS-CoV infection did not affect virus production.
T35 527-694 Sentence denotes However, when CQ was added 1 h before MERS-CoV infection, 16 μm and 32 μM concentrations of CQ could reduce the virus production of 1-log and 2-log, respectively [10].

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
154 200-202 Gene denotes μM Gene:56925
155 260-262 Gene denotes μM Gene:56925
156 598-600 Gene denotes μM Gene:56925
157 588-590 Gene denotes μm Gene:56925
158 183-185 Gene denotes μM Gene:56925
159 37-45 Species denotes MERS-CoV Tax:1335626
160 50-59 Species denotes HCoV-229E Tax:11137
161 80-85 Species denotes human Tax:9606
162 406-414 Species denotes MERS-CoV Tax:1335626
163 368-370 Chemical denotes CQ MESH:D002738
164 446-448 Chemical denotes CQ MESH:D002738
165 541-543 Chemical denotes CQ MESH:D002738
166 619-621 Chemical denotes CQ MESH:D002738
167 86-94 Disease denotes hepatoma MESH:D006528
168 475-493 Disease denotes MERS-CoV infection MESH:D018352
169 570-583 Disease denotes CoV infection MESH:D018352
170 106-111 CellLine denotes Huh-7 CVCL:0336
171 452-458 CellLine denotes VeroE6 CVCL:0574

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T20 4-13 http://purl.obolibrary.org/obo/IDO_0000559 denotes antiviral
T21 95-99 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T22 415-426 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T23 459-464 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T24 484-493 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T25 509-514 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T26 515-525 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T27 574-583 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T28 639-644 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T29 645-655 http://purl.obolibrary.org/obo/IDO_0000607 denotes production

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T11 95-99 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 459-464 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T34 86-94 Disease denotes hepatoma http://purl.obolibrary.org/obo/MONDO_0007256
T35 484-493 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T36 574-583 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
154 200-202 Gene denotes μM Gene:56925
155 260-262 Gene denotes μM Gene:56925
156 598-600 Gene denotes μM Gene:56925
157 588-590 Gene denotes μm Gene:56925
158 183-185 Gene denotes μM Gene:56925
159 37-45 Species denotes MERS-CoV Tax:1335626
160 50-59 Species denotes HCoV-229E Tax:11137
161 80-85 Species denotes human Tax:9606
162 406-414 Species denotes MERS-CoV Tax:1335626
163 368-370 Chemical denotes CQ MESH:D002738
164 446-448 Chemical denotes CQ MESH:D002738
165 541-543 Chemical denotes CQ MESH:D002738
166 619-621 Chemical denotes CQ MESH:D002738
167 86-94 Disease denotes hepatoma MESH:D006528
168 475-493 Disease denotes MERS-CoV infection MESH:D018352
169 570-583 Disease denotes CoV infection MESH:D018352
170 106-111 CellLine denotes Huh-7 CVCL:0336
171 452-458 CellLine denotes VeroE6 CVCL:0574

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T32 0-367 Sentence denotes The antiviral activity of CQ against MERS-CoV and HCoV-229E was assessed in the human hepatoma cell line (Huh-7) and found that the 50% effective concentrations (EC50) were 3.0(±1.1) μM and 3.3(±1.2) μM, the 50% cytotoxic concentrations (CC50) were 58.1(±1.1) μM and >50, and the selectivity indexes (SI; calculated as CC50/EC50) were 19.4 and >15, respectively [10].
T33 368-433 Sentence denotes CQ could inhibit an early step in the MERS-CoV replication cycle.
T34 434-526 Sentence denotes Addition of CQ to VeroE6 cells 1 h after MERS-CoV infection did not affect virus production.
T35 527-694 Sentence denotes However, when CQ was added 1 h before MERS-CoV infection, 16 μm and 32 μM concentrations of CQ could reduce the virus production of 1-log and 2-log, respectively [10].

2_test

Id Subject Object Predicate Lexical cue
32496926-24841269-132195655 363-365 24841269 denotes 10
32496926-24841269-132195656 690-692 24841269 denotes 10