PMC:7441788 / 129-760
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 253-262 | Body_part | denotes | malarials | http://purl.org/sig/ont/fma/fma46831 |
| T2 | 435-443 | Body_part | denotes | endosome | http://purl.org/sig/ont/fma/fma67180 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T3 | 14-38 | Disease | denotes | Coronavirus Disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 40-48 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 61-108 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 61-94 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 110-118 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 201-209 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 349-357 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 614-622 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 481-489 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T2 | 527-535 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T3 | 590-591 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 624-625 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T5 | 221-226 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T6 | 264-275 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T7 | 277-279 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T8 | 285-303 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T9 | 359-361 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-sample-MedDRA
| Id | Subject | Object | Predicate | Lexical cue | meddra_id |
|---|---|---|---|---|---|
| T1 | 233-246 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | investigation | http://purl.bioontology.org/ontology/MEDDRA/10062026 |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T3 | 264-275 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T4 | 277-279 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T5 | 285-303 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T6 | 359-361 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T2 | 14-38 | Species | denotes | Coronavirus Disease 2019 | NCBItxid:2697049 |
| T3 | 40-48 | Species | denotes | COVID-19 | NCBItxid:2697049 |
| T4 | 61-108 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | NCBItxid:2697049 |
| T5 | 110-120 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
| T6 | 201-209 | Species | denotes | COVID-19 | NCBItxid:2697049 |
| T7 | 349-357 | Species | denotes | COVID-19 | NCBItxid:2697049 |
| T8 | 614-622 | Species | denotes | COVID-19 | NCBItxid:2697049 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 5-13 | Sentence | denotes | ABSTRACT |
| T7 | 14-146 | Sentence | denotes | Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. |
| T8 | 147-210 | Sentence | denotes | Antiviral therapy is the most important treatment for COVID-19. |
| T9 | 211-358 | Sentence | denotes | Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. |
| T10 | 359-536 | Sentence | denotes | CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and exhibit immunomodulatory activity. |
| T11 | 537-623 | Sentence | denotes | These multiple mechanisms may work together to exert a therapeutic effect on COVID-19. |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 41 | 61-108 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 42 | 110-120 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 43 | 412-425 | Species | denotes | coronaviruses | Tax:11118 |
| 48 | 264-275 | Chemical | denotes | chloroquine | MESH:D002738 |
| 49 | 277-279 | Chemical | denotes | CQ | MESH:D002738 |
| 50 | 285-303 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 51 | 305-308 | Chemical | denotes | HCQ | MESH:D006886 |
| 63 | 14-38 | Disease | denotes | Coronavirus Disease 2019 | MESH:C000657245 |
| 64 | 40-48 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 65 | 201-209 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 66 | 349-357 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 67 | 614-622 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-33 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | Disease |
| T2 | 147-156 | http://purl.obolibrary.org/obo/IDO_0000559 | denotes | Antiviral |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 253-262 | Body_part | denotes | malarials | http://purl.org/sig/ont/fma/fma46831 |
| T2 | 435-443 | Body_part | denotes | endosome | http://purl.org/sig/ont/fma/fma67180 |
LitCovid-sample-PD-GO-BP-0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 444-457 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
| T2 | 481-496 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T2 | 14-38 | Disease | denotes | Coronavirus Disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 40-48 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 61-108 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 110-120 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 201-209 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 349-357 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 614-622 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sample-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 444-457 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
| T2 | 481-496 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 444-457 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
| T2 | 481-496 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 41 | 61-108 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 42 | 110-120 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 43 | 412-425 | Species | denotes | coronaviruses | Tax:11118 |
| 48 | 264-275 | Chemical | denotes | chloroquine | MESH:D002738 |
| 49 | 277-279 | Chemical | denotes | CQ | MESH:D002738 |
| 50 | 285-303 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 51 | 305-308 | Chemical | denotes | HCQ | MESH:D006886 |
| 63 | 14-38 | Disease | denotes | Coronavirus Disease 2019 | MESH:C000657245 |
| 64 | 40-48 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 65 | 201-209 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 66 | 349-357 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 67 | 614-622 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 5-13 | Sentence | denotes | ABSTRACT |
| T7 | 14-146 | Sentence | denotes | Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. |
| T8 | 147-210 | Sentence | denotes | Antiviral therapy is the most important treatment for COVID-19. |
| T9 | 211-358 | Sentence | denotes | Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. |
| T10 | 359-536 | Sentence | denotes | CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and exhibit immunomodulatory activity. |
| T11 | 537-623 | Sentence | denotes | These multiple mechanisms may work together to exert a therapeutic effect on COVID-19. |