PMC:7441777 / 4274-4654 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T18","span":{"begin":158,"end":161},"obj":"Body_part"}],"attributes":[{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T27","span":{"begin":65,"end":73},"obj":"Disease"},{"id":"T28","span":{"begin":340,"end":348},"obj":"Disease"},{"id":"T29","span":{"begin":351,"end":360},"obj":"Disease"}],"attributes":[{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T26","span":{"begin":263,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T27","span":{"begin":286,"end":287},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T42","span":{"begin":94,"end":108},"obj":"Chemical"},{"id":"T43","span":{"begin":94,"end":103},"obj":"Chemical"},{"id":"T44","span":{"begin":104,"end":108},"obj":"Chemical"},{"id":"T45","span":{"begin":312,"end":322},"obj":"Chemical"}],"attributes":[{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_36044"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A44","pred":"chebi_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A45","pred":"chebi_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"171","span":{"begin":57,"end":61},"obj":"Gene"},{"id":"180","span":{"begin":65,"end":75},"obj":"Species"},{"id":"184","span":{"begin":110,"end":120},"obj":"Chemical"},{"id":"185","span":{"begin":242,"end":252},"obj":"Chemical"},{"id":"187","span":{"begin":340,"end":360},"obj":"Disease"}],"attributes":[{"id":"A171","pred":"tao:has_database_id","subj":"171","obj":"Gene:43740578"},{"id":"A180","pred":"tao:has_database_id","subj":"180","obj":"Tax:2697049"},{"id":"A184","pred":"tao:has_database_id","subj":"184","obj":"MESH:C000606551"},{"id":"A185","pred":"tao:has_database_id","subj":"185","obj":"MESH:C000606551"},{"id":"A187","pred":"tao:has_database_id","subj":"187","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T37","span":{"begin":0,"end":380},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Very recently, Yin et al. reported the crystal structure RdRp of SARS-CoV-2 complexed with an antiviral drug, Remdesivir highlighting how the template-primer RNA is recognized by the polymerase enzyme and the chain elongation is inhibited by Remdesivir providing a basis for developing a wide range of effective inhibitors to overcome from SARS-CoV-2 infection (Yin et al., 2020)."}