PMC:7441777 / 18278-18758 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7441777","sourcedb":"PMC","sourceid":"7441777","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7441777","text":"2.4. ADMET studies\nThe in-silico pharmacological studies of EGCG, TF2a, TF2b, TF3, and remdesivir were predicted based on their ADMET profile. The ADMET studies (absorption, distribution, metabolism, elimination, and toxicity) were predicted using the pkCSM tool (http://biosig.unimelb.edu.au/pkcsm/prediction) (Pires et al., 2015). The canonical SMILE molecular structures of the above-mentioned compounds were retrieved from the PubChem database (www.pubchem.ncbi.nlm.nih.gov).","divisions":[{"label":"label","span":{"begin":0,"end":4}},{"label":"title","span":{"begin":6,"end":19}}],"tracks":[{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T263","span":{"begin":61,"end":65},"obj":"Chemical"},{"id":"T264","span":{"begin":79,"end":82},"obj":"Chemical"},{"id":"T265","span":{"begin":88,"end":98},"obj":"Chemical"}],"attributes":[{"id":"A263","pred":"chebi_id","subj":"T263","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A264","pred":"chebi_id","subj":"T264","obj":"http://purl.obolibrary.org/obo/CHEBI_136608"},{"id":"A265","pred":"chebi_id","subj":"T265","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"subj":"T263","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T264","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T265","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T7","span":{"begin":189,"end":199},"obj":"http://purl.obolibrary.org/obo/GO_0008152"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"398","span":{"begin":73,"end":77},"obj":"Gene"},{"id":"399","span":{"begin":61,"end":65},"obj":"Chemical"},{"id":"400","span":{"begin":88,"end":98},"obj":"Chemical"},{"id":"401","span":{"begin":218,"end":226},"obj":"Disease"}],"attributes":[{"id":"A398","pred":"tao:has_database_id","subj":"398","obj":"Gene:2959"},{"id":"A399","pred":"tao:has_database_id","subj":"399","obj":"MESH:C045651"},{"id":"A400","pred":"tao:has_database_id","subj":"400","obj":"MESH:C000606551"},{"id":"A401","pred":"tao:has_database_id","subj":"401","obj":"MESH:D064420"},{"subj":"398","pred":"source","obj":"LitCovid-PubTator"},{"subj":"399","pred":"source","obj":"LitCovid-PubTator"},{"subj":"400","pred":"source","obj":"LitCovid-PubTator"},{"subj":"401","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T181","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T182","span":{"begin":6,"end":19},"obj":"Sentence"},{"id":"T183","span":{"begin":20,"end":143},"obj":"Sentence"},{"id":"T184","span":{"begin":144,"end":333},"obj":"Sentence"},{"id":"T185","span":{"begin":334,"end":480},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T181","pred":"source","obj":"LitCovid-sentences"},{"subj":"T182","pred":"source","obj":"LitCovid-sentences"},{"subj":"T183","pred":"source","obj":"LitCovid-sentences"},{"subj":"T184","pred":"source","obj":"LitCovid-sentences"},{"subj":"T185","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32720577-25860834-56195124","span":{"begin":327,"end":331},"obj":"25860834"}],"attributes":[{"subj":"32720577-25860834-56195124","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-CHEBI","color":"#ec93eb","default":true},{"id":"LitCovid-PD-GO-BP","color":"#93ecd2"},{"id":"LitCovid-PubTator","color":"#ecb893"},{"id":"LitCovid-sentences","color":"#9e93ec"},{"id":"2_test","color":"#a1ec93"}]}]}}