PMC:7435837 / 2593-3477 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7435837","sourcedb":"PMC","sourceid":"7435837","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7435837","text":"Encapsulated viruses such as the SARS-CoV and SARS-CoV-2 viruses comprise of some general surface constituents. The surface envelope or capsule is presented as a lipid bilayer membrane that contains various envelope proteins (E), membrane proteins (M), and an outer layer that presents so-called spike (S) proteins [1]. M and S proteins are generally rich in sugar molecules that form a so-called glycan structure. N- or O-glycosylate moieties are commonly found in the viral S proteins and they can recognize some cell receptors to which the virion can bind [2,3]. These spike proteins facilitate virion entry into host cells. Encapsulated viruses such as the coronaviruses present approximately 200 of these spiky structures [4]. Spike proteins are comprised of glycoproteins, proteins that also contain polysaccharide or oligosaccharide moieties otherwise known as glycans 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