PMC:7417788 / 25640-25984 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T602","span":{"begin":9,"end":16},"obj":"PR:000005559"},{"id":"T603","span":{"begin":21,"end":26},"obj":"PR:000016867"},{"id":"T604","span":{"begin":55,"end":62},"obj":"CHEBI:59132;CHEBI:59132;GO:0019882"},{"id":"T605","span":{"begin":62,"end":75},"obj":"GO:0019882"},{"id":"T606","span":{"begin":97,"end":103},"obj":"PR:000010094"},{"id":"T607","span":{"begin":108,"end":111},"obj":"PR:000003858"},{"id":"T608","span":{"begin":294,"end":301},"obj":"CHEBI:59132;CHEBI:59132;GO:0019882"},{"id":"T609","span":{"begin":301,"end":312},"obj":"GO:0019882"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T504","span":{"begin":88,"end":91},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T505","span":{"begin":156,"end":159},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T506","span":{"begin":211,"end":215},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T507","span":{"begin":236,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0001627"},{"id":"T508","span":{"begin":239,"end":242},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T509","span":{"begin":329,"end":332},"obj":"http://purl.obolibrary.org/obo/CL_0000451"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T158","span":{"begin":55,"end":62},"obj":"Chemical"},{"id":"T159","span":{"begin":236,"end":238},"obj":"Chemical"},{"id":"T161","span":{"begin":294,"end":301},"obj":"Chemical"}],"attributes":[{"id":"A158","pred":"chebi_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A159","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_15843"},{"id":"A160","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_72816"},{"id":"A161","pred":"chebi_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T138","span":{"begin":55,"end":75},"obj":"http://purl.obolibrary.org/obo/GO_0019882"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T129","span":{"begin":0,"end":344},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"2_test","denotations":[{"id":"32780218-29706550-132718696","span":{"begin":173,"end":177},"obj":"29706550"},{"id":"32780218-29706550-132718697","span":{"begin":194,"end":198},"obj":"29706550"},{"id":"32780218-29706550-132718698","span":{"begin":211,"end":215},"obj":"29706550"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"566","span":{"begin":9,"end":16},"obj":"Gene"},{"id":"567","span":{"begin":21,"end":26},"obj":"Gene"},{"id":"568","span":{"begin":97,"end":103},"obj":"Gene"},{"id":"569","span":{"begin":108,"end":111},"obj":"Gene"},{"id":"571","span":{"begin":263,"end":266},"obj":"Mutation"}],"attributes":[{"id":"A566","pred":"tao:has_database_id","subj":"566","obj":"Gene:160364"},{"id":"A567","pred":"tao:has_database_id","subj":"567","obj":"Gene:10628"},{"id":"A568","pred":"tao:has_database_id","subj":"568","obj":"Gene:378938"},{"id":"A569","pred":"tao:has_database_id","subj":"569","obj":"Gene:196"},{"id":"A571","pred":"tao:has_standard_notation","subj":"571","obj":"p.S7I"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Notably, CLEC12A and TXNIP, which are critical for the antigen-presentation function of DCs; and MALAT1 and AHR, which are critical to inducing tolerogenic DCs (Son et al., 2008; Hutten et al., 2016; Wu et al., 2018), were decreased in AA DCs (Figs. 3I, S7G, and S7I), reflecting the decreased antigen-presenting ability of aged DCs (Fig. S7H)."}