PMC:7408073 / 61754-62083 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"2230","span":{"begin":26,"end":30},"obj":"Gene"},{"id":"2231","span":{"begin":36,"end":39},"obj":"Gene"},{"id":"2232","span":{"begin":155,"end":159},"obj":"Gene"},{"id":"2233","span":{"begin":165,"end":168},"obj":"Gene"},{"id":"2234","span":{"begin":249,"end":253},"obj":"Gene"},{"id":"2237","span":{"begin":187,"end":191},"obj":"Chemical"},{"id":"2238","span":{"begin":282,"end":286},"obj":"Chemical"}],"attributes":[{"id":"A2230","pred":"tao:has_database_id","subj":"2230","obj":"Gene:59272"},{"id":"A2231","pred":"tao:has_database_id","subj":"2231","obj":"Gene:59272"},{"id":"A2232","pred":"tao:has_database_id","subj":"2232","obj":"Gene:59272"},{"id":"A2233","pred":"tao:has_database_id","subj":"2233","obj":"Gene:59272"},{"id":"A2234","pred":"tao:has_database_id","subj":"2234","obj":"Gene:59272"},{"id":"A2237","pred":"tao:has_database_id","subj":"2237","obj":"MESH:D004492"},{"id":"A2238","pred":"tao:has_database_id","subj":"2238","obj":"MESH:D004492"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE). In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79]. Of interest, EDTA binds with 106- and 102-fold higher affini"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T779","span":{"begin":193,"end":194},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T780","span":{"begin":212,"end":215},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T781","span":{"begin":254,"end":262},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T782","span":{"begin":307,"end":310},"obj":"http://purl.obolibrary.org/obo/CLO_0054060"}],"text":"ternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE). In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79]. Of interest, EDTA binds with 106- and 102-fold higher affini"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T73784","span":{"begin":71,"end":77},"obj":"Chemical"},{"id":"T52408","span":{"begin":78,"end":83},"obj":"Chemical"},{"id":"T48403","span":{"begin":134,"end":138},"obj":"Chemical"},{"id":"T22224","span":{"begin":187,"end":191},"obj":"Chemical"},{"id":"T5627","span":{"begin":195,"end":201},"obj":"Chemical"},{"id":"T70245","span":{"begin":202,"end":210},"obj":"Chemical"},{"id":"T22254","span":{"begin":282,"end":286},"obj":"Chemical"}],"attributes":[{"id":"A69592","pred":"chebi_id","subj":"T73784","obj":"http://purl.obolibrary.org/obo/CHEBI_36916"},{"id":"A74244","pred":"chebi_id","subj":"T52408","obj":"http://purl.obolibrary.org/obo/CHEBI_22563"},{"id":"A53277","pred":"chebi_id","subj":"T48403","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A61554","pred":"chebi_id","subj":"T48403","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"},{"id":"A82198","pred":"chebi_id","subj":"T22224","obj":"http://purl.obolibrary.org/obo/CHEBI_42191"},{"id":"A99290","pred":"chebi_id","subj":"T22224","obj":"http://purl.obolibrary.org/obo/CHEBI_64755"},{"id":"A88469","pred":"chebi_id","subj":"T5627","obj":"http://purl.obolibrary.org/obo/CHEBI_36916"},{"id":"A38655","pred":"chebi_id","subj":"T70245","obj":"http://purl.obolibrary.org/obo/CHEBI_38161"},{"id":"A59843","pred":"chebi_id","subj":"T22254","obj":"http://purl.obolibrary.org/obo/CHEBI_42191"},{"id":"A54595","pred":"chebi_id","subj":"T22254","obj":"http://purl.obolibrary.org/obo/CHEBI_64755"}],"text":"ternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE). In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79]. Of interest, EDTA binds with 106- and 102-fold higher affini"}

{"project":"LitCovid-sentences","denotations":[{"id":"T297","span":{"begin":171,"end":268},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE). In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79]. Of interest, EDTA binds with 106- and 102-fold higher affini"}