ternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE). In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79]. Of interest, EDTA binds with 106- and 102-fold higher affini