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PMC:7408073 / 30291-30662 JSONTXT

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LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T61 99-123 Body_part denotes renin–angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1097 136-141 Gene denotes renin Gene:5972
1098 143-146 Gene denotes ACE Gene:59272
1099 151-155 Gene denotes ACE2 Gene:59272
1100 226-234 Gene denotes Ang (1–9 Gene:284
1101 237-245 Gene denotes Ang (1–5 Gene:284
1102 275-285 Gene denotes bradykinin Gene:3827
1103 317-321 Gene denotes ACE2 Gene:59272
1104 215-223 Gene denotes Ang (1–7 Gene:284
1105 354-364 Species denotes SARS-CoV-2 Tax:2697049
1106 99-104 Gene denotes renin Gene:5972
1107 207-213 Gene denotes Ang II Gene:24179
1108 4-11 Disease denotes Hypoxia MESH:D000860
1109 39-50 Disease denotes hypercapnia MESH:D006935

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T206 354-362 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T207 354-358 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T371 70-78 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T372 87-91 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T373 302-310 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T258 105-116 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T259 200-203 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T260 207-210 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T261 211-213 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T262 215-218 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T263 226-229 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T264 237-240 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T265 264-274 Chemical denotes metabolite http://purl.obolibrary.org/obo/CHEBI_25212
T266 275-285 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T55 156-165 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T143 0-371 Sentence denotes (2) Hypoxia in combination or not with hypercapnia can upregulate the activity of both arms of the renin–angiotensin system by inducing renin, ACE and ACE2 synthesis, which can increase expression of Ang I, Ang II, Ang (1–7), Ang (1–9), Ang (1–5) and the inactive metabolite bradykinin (1–7), but also membrane bound ACE2, finally giving more chances to SARS-CoV-2 entry.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T53 4-11 Phenotype denotes Hypoxia http://purl.obolibrary.org/obo/HP_0012418
T54 39-50 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416