PMC:7408073 / 27115-27412 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T56","span":{"begin":55,"end":58},"obj":"Body_part"}],"attributes":[{"id":"A56","pred":"uberon_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1039","span":{"begin":232,"end":236},"obj":"Gene"},{"id":"1040","span":{"begin":256,"end":264},"obj":"Gene"},{"id":"1044","span":{"begin":117,"end":125},"obj":"Gene"},{"id":"1049","span":{"begin":281,"end":285},"obj":"Gene"},{"id":"1056","span":{"begin":95,"end":105},"obj":"Species"},{"id":"1058","span":{"begin":127,"end":133},"obj":"Gene"},{"id":"1069","span":{"begin":19,"end":37},"obj":"Disease"}],"attributes":[{"id":"A1039","pred":"tao:has_database_id","subj":"1039","obj":"Gene:59272"},{"id":"A1040","pred":"tao:has_database_id","subj":"1040","obj":"Gene:284"},{"id":"A1044","pred":"tao:has_database_id","subj":"1044","obj":"Gene:284"},{"id":"A1049","pred":"tao:has_database_id","subj":"1049","obj":"Gene:116511"},{"id":"A1056","pred":"tao:has_database_id","subj":"1056","obj":"Tax:2697049"},{"id":"A1058","pred":"tao:has_database_id","subj":"1058","obj":"Gene:24179"},{"id":"A1069","pred":"tao:has_database_id","subj":"1069","obj":"MESH:D000071069"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T174","span":{"begin":95,"end":103},"obj":"Disease"},{"id":"T175","span":{"begin":95,"end":99},"obj":"Disease"}],"attributes":[{"id":"A174","pred":"mondo_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A175","pred":"mondo_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T341","span":{"begin":43,"end":47},"obj":"http://www.ebi.ac.uk/efo/EFO_0001410"},{"id":"T342","span":{"begin":246,"end":254},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T343","span":{"begin":286,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T237","span":{"begin":55,"end":58},"obj":"Chemical"},{"id":"T238","span":{"begin":117,"end":120},"obj":"Chemical"},{"id":"T239","span":{"begin":127,"end":130},"obj":"Chemical"},{"id":"T240","span":{"begin":131,"end":133},"obj":"Chemical"},{"id":"T241","span":{"begin":256,"end":259},"obj":"Chemical"}],"attributes":[{"id":"A237","pred":"chebi_id","subj":"T237","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A238","pred":"chebi_id","subj":"T238","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A239","pred":"chebi_id","subj":"T239","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A240","pred":"chebi_id","subj":"T240","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A241","pred":"chebi_id","subj":"T241","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}

{"project":"LitCovid-sentences","denotations":[{"id":"T126","span":{"begin":0,"end":297},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation."}