PMC:7402624 / 373-1006 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":47,"end":51},"obj":"Body_part"},{"id":"T2","span":{"begin":58,"end":62},"obj":"Body_part"},{"id":"T3","span":{"begin":129,"end":133},"obj":"Body_part"},{"id":"T4","span":{"begin":189,"end":200},"obj":"Body_part"},{"id":"T5","span":{"begin":242,"end":247},"obj":"Body_part"},{"id":"T6","span":{"begin":279,"end":289},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma84371"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma62863"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}

{"project":"LitCovid-PubTator","denotations":[{"id":"14","span":{"begin":90,"end":98},"obj":"Species"},{"id":"15","span":{"begin":114,"end":122},"obj":"Species"},{"id":"18","span":{"begin":169,"end":184},"obj":"Disease"}],"attributes":[{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"Tax:9606"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"Tax:9606"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:D001102"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T4","span":{"begin":169,"end":184},"obj":"Disease"},{"id":"T5","span":{"begin":175,"end":184},"obj":"Disease"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T4","span":{"begin":31,"end":41},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T5","span":{"begin":45,"end":51},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T6","span":{"begin":56,"end":62},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T7","span":{"begin":74,"end":75},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T8","span":{"begin":100,"end":101},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T9","span":{"begin":127,"end":133},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T10","span":{"begin":134,"end":144},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T11","span":{"begin":240,"end":247},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T12","span":{"begin":290,"end":300},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":127,"end":144},"obj":"http://purl.obolibrary.org/obo/GO_0042110"},{"id":"T3","span":{"begin":129,"end":144},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T4","span":{"begin":169,"end":184},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T5","span":{"begin":279,"end":300},"obj":"http://purl.obolibrary.org/obo/GO_0046649"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}

{"project":"LitCovid-sentences","denotations":[{"id":"T6","span":{"begin":100,"end":248},"obj":"Sentence"},{"id":"T7","span":{"begin":249,"end":335},"obj":"Sentence"},{"id":"T8","span":{"begin":336,"end":453},"obj":"Sentence"},{"id":"T9","span":{"begin":454,"end":567},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching \u003e30% of circulating B cells. However, another subgroup had lymphocyte activation comparable to uninfected subjects. Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. These immunotypes may have implications for the design of therape"}