PMC:7386875 / 742-1228 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":38,"end":55},"obj":"Body_part"},{"id":"T2","span":{"begin":50,"end":55},"obj":"Body_part"},{"id":"T3","span":{"begin":127,"end":143},"obj":"Body_part"},{"id":"T4","span":{"begin":139,"end":143},"obj":"Body_part"},{"id":"T5","span":{"begin":273,"end":281},"obj":"Body_part"},{"id":"T6","span":{"begin":287,"end":296},"obj":"Body_part"},{"id":"T7","span":{"begin":465,"end":469},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma50723"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":460,"end":469},"obj":"Body_part"},{"id":"T2","span":{"begin":465,"end":469},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0035552"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0001638"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T15","span":{"begin":17,"end":25},"obj":"Disease"},{"id":"T16","span":{"begin":179,"end":187},"obj":"Disease"},{"id":"T17","span":{"begin":215,"end":227},"obj":"Disease"},{"id":"T18","span":{"begin":470,"end":480},"obj":"Disease"}],"attributes":[{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0000831"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T5","span":{"begin":38,"end":55},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T6","span":{"begin":127,"end":143},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T7","span":{"begin":240,"end":250},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T8","span":{"begin":465,"end":469},"obj":"http://purl.obolibrary.org/obo/UBERON_0001638"},{"id":"T9","span":{"begin":465,"end":469},"obj":"http://www.ebi.ac.uk/efo/EFO_0000816"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":67,"end":78},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":460,"end":480},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002625"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":215,"end":227},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T2","span":{"begin":229,"end":250},"obj":"http://purl.obolibrary.org/obo/GO_0006956"},{"id":"T3","span":{"begin":343,"end":368},"obj":"http://purl.obolibrary.org/obo/GO_0002250"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}

{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":60,"end":65},"obj":"Gene"},{"id":"49","span":{"begin":67,"end":98},"obj":"Gene"},{"id":"50","span":{"begin":252,"end":260},"obj":"Gene"},{"id":"53","span":{"begin":17,"end":27},"obj":"Species"},{"id":"54","span":{"begin":165,"end":173},"obj":"Species"},{"id":"72","span":{"begin":179,"end":187},"obj":"Disease"},{"id":"73","span":{"begin":215,"end":227},"obj":"Disease"},{"id":"74","span":{"begin":382,"end":398},"obj":"Disease"},{"id":"75","span":{"begin":426,"end":450},"obj":"Disease"},{"id":"76","span":{"begin":460,"end":480},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Gene:59272"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:59272"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Gene:2147"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Tax:2697049"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:9606"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D007249"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"MESH:D013927"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"MESH:D020246"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"o the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulm"}