PMC:7386875 / 25655-26234 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T227","span":{"begin":46,"end":55},"obj":"Body_part"},{"id":"T228","span":{"begin":82,"end":90},"obj":"Body_part"}],"attributes":[{"id":"A227","pred":"fma_id","subj":"T227","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A228","pred":"fma_id","subj":"T228","obj":"http://purl.org/sig/ont/fma/fma62851"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T210","span":{"begin":32,"end":40},"obj":"Disease"},{"id":"T211","span":{"begin":99,"end":115},"obj":"Disease"},{"id":"T212","span":{"begin":164,"end":172},"obj":"Disease"},{"id":"T213","span":{"begin":220,"end":236},"obj":"Disease"},{"id":"T214","span":{"begin":325,"end":341},"obj":"Disease"},{"id":"T215","span":{"begin":352,"end":360},"obj":"Disease"},{"id":"T216","span":{"begin":453,"end":469},"obj":"Disease"},{"id":"T217","span":{"begin":492,"end":500},"obj":"Disease"}],"attributes":[{"id":"A210","pred":"mondo_id","subj":"T210","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A211","pred":"mondo_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/MONDO_0002049"},{"id":"A212","pred":"mondo_id","subj":"T212","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A213","pred":"mondo_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/MONDO_0002049"},{"id":"A214","pred":"mondo_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/MONDO_0002049"},{"id":"A215","pred":"mondo_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A216","pred":"mondo_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/MONDO_0002049"},{"id":"A217","pred":"mondo_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T238","span":{"begin":116,"end":119},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T239","span":{"begin":137,"end":138},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T240","span":{"begin":178,"end":179},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T241","span":{"begin":257,"end":258},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T242","span":{"begin":403,"end":404},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T243","span":{"begin":473,"end":474},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T43","span":{"begin":99,"end":115},"obj":"Phenotype"},{"id":"T44","span":{"begin":220,"end":236},"obj":"Phenotype"},{"id":"T45","span":{"begin":325,"end":341},"obj":"Phenotype"},{"id":"T46","span":{"begin":453,"end":469},"obj":"Phenotype"}],"attributes":[{"id":"A43","pred":"hp_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/HP_0001873"},{"id":"A44","pred":"hp_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/HP_0001873"},{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0001873"},{"id":"A46","pred":"hp_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/HP_0001873"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"LitCovid-sentences","denotations":[{"id":"T96","span":{"begin":0,"end":98},"obj":"Sentence"},{"id":"T97","span":{"begin":99,"end":579},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"2_test","denotations":[{"id":"32586214-32109013-21597730","span":{"begin":299,"end":301},"obj":"32109013"},{"id":"32586214-32171076-21597731","span":{"begin":302,"end":304},"obj":"32171076"},{"id":"32586214-32178975-21597732","span":{"begin":305,"end":307},"obj":"32178975"},{"id":"32586214-32302435-21597733","span":{"begin":308,"end":310},"obj":"32302435"},{"id":"32586214-32178975-21597734","span":{"begin":442,"end":444},"obj":"32178975"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}

{"project":"LitCovid-PubTator","denotations":[{"id":"919","span":{"begin":32,"end":42},"obj":"Species"},{"id":"920","span":{"begin":492,"end":502},"obj":"Species"},{"id":"921","span":{"begin":99,"end":115},"obj":"Disease"},{"id":"922","span":{"begin":164,"end":172},"obj":"Disease"},{"id":"923","span":{"begin":220,"end":236},"obj":"Disease"},{"id":"924","span":{"begin":325,"end":341},"obj":"Disease"},{"id":"925","span":{"begin":352,"end":360},"obj":"Disease"},{"id":"926","span":{"begin":433,"end":441},"obj":"Disease"},{"id":"927","span":{"begin":453,"end":469},"obj":"Disease"}],"attributes":[{"id":"A919","pred":"tao:has_database_id","subj":"919","obj":"Tax:2697049"},{"id":"A920","pred":"tao:has_database_id","subj":"920","obj":"Tax:2697049"},{"id":"A921","pred":"tao:has_database_id","subj":"921","obj":"MESH:D013921"},{"id":"A922","pred":"tao:has_database_id","subj":"922","obj":"MESH:C000657245"},{"id":"A923","pred":"tao:has_database_id","subj":"923","obj":"MESH:D013921"},{"id":"A924","pred":"tao:has_database_id","subj":"924","obj":"MESH:D013921"},{"id":"A925","pred":"tao:has_database_id","subj":"925","obj":"MESH:C000657245"},{"id":"A926","pred":"tao:has_database_id","subj":"926","obj":"MESH:C000657245"},{"id":"A927","pred":"tao:has_database_id","subj":"927","obj":"MESH:D013921"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The most well-studied effect of SARS-CoV-2 on platelets pertains to its effect on platelet number. Thrombocytopenia has been reported as a common finding in severe COVID-19 with a recent meta-analysis demonstrating that thrombocytopenia was associated with a 5-fold increased risk of severe disease.14,16,73,74 The degree of thrombocytopenia in severe COVID-19 is usually mild and does not appear to be a common feature in nonsevere COVID-19.73 Whether thrombocytopenia is a direct effect of SARS-CoV-2 or multifactorial in the setting of severe illness remains to be elucidated."}