PMC:7386875 / 18629-19343
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T119 | 219-222 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T120 | 314-324 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
| T121 | 329-338 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T122 | 356-361 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T123 | 450-453 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T124 | 669-677 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T184 | 388-396 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T185 | 552-560 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T186 | 583-591 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T187 | 705-713 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T158 | 356-361 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T159 | 399-402 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T81 | 211-214 | Chemical | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 |
| T83 | 219-222 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T38 | 669-683 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T40 | 631-644 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T78 | 0-714 | Sentence | denotes | PRR (Pattern recognition receptors), such as TLR (Toll-like receptors), subsequently detect the release of pathogen-associated molecular patterns, and intracellular danger-associated molecular patterns, such as ATP and DNA, which evokes an intense inflammatory reaction and triggers the release of proinflammatory chemokines and cytokines from neighboring cells (Figure 1).46 Strikingly, SARS-CoV-2 has been found to contain multiple single-stranded RNA fragments that can be recognized by TLR-7 and TLR-8, similar in numbers to MERS-CoV but more than SARS-CoV.47 The recognition of SARS-CoV-2 by these receptors may contribute to innate immune hyperactivation and the cytokine storm often seen in severe COVID-19. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32586214-32346093-21597701 | 373-375 | 32346093 | denotes | 46 |
| 32586214-32361001-21597702 | 561-563 | 32361001 | denotes | 47 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 709 | 490-495 | Gene | denotes | TLR-7 | Gene:51284 |
| 710 | 500-505 | Gene | denotes | TLR-8 | Gene:51311 |
| 713 | 388-398 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 714 | 529-537 | Species | denotes | MERS-CoV | Tax:1335626 |
| 715 | 552-560 | Species | denotes | SARS-CoV | Tax:694009 |
| 716 | 583-593 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 717 | 211-214 | Chemical | denotes | ATP | MESH:D000255 |
| 721 | 705-713 | Disease | denotes | COVID-19 | MESH:C000657245 |